rs10273639
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis.
|
31163246 |
2020 |
rs10273639
|
|
|
0.820 |
GeneticVariation |
BEFREE |
While rs62228256 was not validated as a risk factor (<i>P</i>=0.77), both rs13228878 (<i>P</i>=0.03) and rs10273639 (<i>P</i>=0.04) were. rs13228878 and rs10273639 are in high linkage disequilibrium (r<sup>2</sup>=0.94) and associated with elevated expression of the <i>PRSS1</i> gene, which encodes for trypsinogen, and are known risk variants for alcohol-associated and sporadic pancreatitis in adults.
|
30467200 |
2019 |
rs10273639
|
|
C |
0.820 |
GeneticVariation |
GWASCAT |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs10273639
|
|
C |
0.820 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs12688220
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis.
|
31163246 |
2020 |
rs12688220
|
|
T |
0.810 |
GeneticVariation |
GWASCAT |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs12688220
|
|
T |
0.810 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs2995271
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs2995271
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs379742
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs379742
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs7057398
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Effects of PRSS1-PRSS2 rs10273639, CLDN2 rs7057398 and MORC4 rs12688220 polymorphisms on individual susceptibility to pancreatitis: A meta-analysis.
|
31163246 |
2020 |
rs7057398
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs4437130
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs62561366
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs12008279
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs12014762
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs4409525
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs5917027
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs6622126
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
|
23143602 |
2012 |
rs201893408
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs74571530
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs752362727
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs886037774
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs886037775
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|