|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Nevertheless, the pooled analyses suggested that no significant association was uncovered between r</span>s11724635 and PD risk (<i>P</i>>0.05).
|
31118642 |
2019 |
|
rs11724635
|
|
A |
0.880 |
GeneticVariation |
GWASCAT |
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.
|
28892059 |
2017 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Here, in order to discover potential AD-related loci, we investigated the association between late-onset AD (LOAD) susceptibility and nine single-nucleotide polymorphisms (SNPs) (rs11724635 of BST1, rs12637471 of MCCC1, rs15553999 of TMEM229, rs17649553 of MAPT, rs34311866 of TMEM175-GAK-DGKQ, rs356182 of SNCA, rs6430538 of ACMSD-TMEM163, rs76904798 of LRRK2 and rs823118 of RAB7L1-NUCKS1) which were reported to have genome-wide significant associations with PD risk in a recent Genome Wide Association Study performed among white population.
|
26738859 |
2017 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The pooled OR of the rs11724635 variant (C→A) indicated a non-significant association with PD in a recessive model (OR, 1.16, 95% CI: 0.97-1.40; P=0.112), dominant model (OR, 1.10, 95% CI: 0.86-1.41; P=0.458) and allelic model (OR, 1.10, 95% CI: 0.95-1.27; P=0.224).
|
25986899 |
2015 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Herein, we investigated the effect of 4 top PD-associated genetic variants in Caucasians listed on the top risk loci identified by meta-analysis of genome wide-association studies in PDGene database (http://www.pdgene.org/top_results), including serine threonine kinase 39 (STK39) rs1955337, bone marrow stromal cell antigen 1 (BST1) rs11724635, major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1) rs9275326, and signal peptide peptidase-like 2B (SPPL2B) rs62120679, by genotyping 596 Han-Chinese patients with PD and 597 age-matched control subjects.
|
26469904 |
2015 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Of note, ever use of well water before the onset of PD symptoms had an impact on the occurrence of PD through interactions with BST1 rs11724635 AC (OR = 1.453, p = 0.024) and CC (OR = 1.623, p = 0.008).
|
24342025 |
2014 |
|
rs11724635
|
|
A |
0.880 |
GeneticVariation |
GWASCAT |
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
|
25064009 |
2014 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The minor allele frequency of rs11724635 produced weaker signals for PD, but this was not replicated in the genotype after adjusting for age and sex.
|
23853107 |
2013 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
|
22451204 |
2012 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
No significant interactions were found between BST1 SNP rs11724635 and smoking or caffeine intake with respect to spo</span>radic PD.
|
23026536 |
2012 |
|
rs11724635
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Subgroup analysis by ethnicity showed significantly stronger effects for the BST1 (rs11724635) in Asian vs Caucasian populations and similar effects for SNCA, LRRK2, LAMP3, HIP1R, and STK39 in Asian and Caucasian populations, while MAPT rs2942168 and SYT11 rs34372695 were monomorphic in the Asian population, highlighting the role of population-specific heterogeneity in PD.
|
22786590 |
2012 |
|
rs11724635
|
|
A |
0.880 |
GeneticVariation |
GWASCAT |
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.
|
21292315 |
2011 |
|
rs11724635
|
|
A |
0.880 |
GeneticVariation |
GWASDB |
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.
|
21292315 |
2011 |