Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE Our current meta-analysis involving the rs12456492(A/G) variant demonstrated that the GG + GA genotypes, GG genotypes, and G allele may be risk factors for PD. 31818509

2020

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE In the study reported here, we investigated the association of the rs12456492 and rs16976358 SNPs of the RIT2 gene with PD, essential tremor (ET), autism, schizophrenia (SCZ), and bipolar disorder (BPD; total of 2290 patients), and 1000 controls, by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 26941103

2017

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE Therefore, more replication studies in additional Chinese population and other cohorts are warranted to further clarify the role of RIT2 rs12456492 in PD susceptibility. 27889863

2017

dbSNP: rs12456492
rs12456492
G 0.890 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. 28892059

2017

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE This study replicates the association between rs12456492 variant and risk of developing PD in a Han Chinese population. 25559334

2015

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE Our data support that the carriage of G allele of rs12456492 variant of RIT2 gene significantly increases the risk for PD in Han Chinese population, suggesting a potential role of RIT2 in the etiology of PD. 25457028

2015

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE RIT2 rs12456492 polymorphism and the risk of Parkinson's disease: A meta-analysis. 26188085

2015

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE The current meta-analysis suggested that rs12456492</span> might be associated with increased PD risk in Asian populations, but studies using larger sample sizes and different ethnic populations will be needed to further confirm this association. 26334395

2015

dbSNP: rs12456492
rs12456492
G 0.890 GeneticVariation GWASCAT Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. 25064009

2014

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE We failed to replicate the RIT2 rs12456492 variant as a genetic risk factor for PD in our population. 23635658

2013

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation GWASDB A novel PD susceptibility locus, RIT2, on chromosome 18 (rs12456492; p=5×10(-5) Discovery Sample; p=1.52×10(-7) Replication sample; p=2×10(-10) Combined Sample) was replicated. 22451204

2012

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation BEFREE A novel PD susceptibility locus, RIT2, on chromosome 18 (rs12456492; p=5×10(-5) Discovery Sample; p=1.52×10(-7) Replication sample; p=2×10(-10) Combined Sample) was replicated. 22451204

2012

dbSNP: rs12456492
rs12456492
0.890 GeneticVariation GWASCAT A novel PD susceptibility locus, RIT2, on chromosome 18 (rs12456492; p=5×10(-5) Discovery Sample; p=1.52×10(-7) Replication sample; p=2×10(-10) Combined Sample) was replicated. 22451204

2012