Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs74315370
rs74315370
SDHB
C 0.800 CausalMutation CLINVAR Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma. 28738844

2017
dbSNP: rs74315370
rs74315370
SDHB
C 0.800 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. 24893135

2014
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 24493721

2014
dbSNP: rs74315370
rs74315370
SDHB
A 0.800 CausalMutation CLINVAR Identification of succinate dehydrogenase-deficient bladder paragangliomas. 23797725

2013
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Canadian guideline on genetic screening for hereditary renal cell cancers. 24319509

2013
dbSNP: rs74315370
rs74315370
SDHB
A 0.800 CausalMutation CLINVAR High prevalence of founder mutations of the succinate dehydrogenase genes in the Netherlands. 21348866

2012
dbSNP: rs74315370
rs74315370
SDHB
C 0.800 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs74315370
rs74315370
SDHB
A 0.800 CausalMutation CLINVAR Germline SDHB mutations and familial renal cell carcinoma. 18728283

2008
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Somatic SDHB mutation in an extraadrenal pheochromocytoma. 17634472

2007
dbSNP: rs74315370
rs74315370
SDHB
A 0.800 CausalMutation CLINVAR In addition all index patients of five families showing hereditary pheochromocytoma-paraganglioma were found to carry germline mutations of SDHB: four of which were novel, c.343C>T (p.Arg115X), c.141G>A (p.Trp47X), c.281G>A (p.Arg94Lys), and c.653G>C (p.Trp218Ser), and one reported previously, c.136C>T, p.Arg46X. 16405730

2006
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004
dbSNP: rs74315370
rs74315370
SDHB
C 0.800 CausalMutation CLINVAR Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. 15328326

2004
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility. 14974914

2003
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003
dbSNP: rs74315370
rs74315370
SDHB
A 0.800 CausalMutation CLINVAR Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. 12618761

2003
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003
dbSNP: rs74315370
rs74315370
SDHB
C 0.800 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Germ-line mutations in nonsyndromic pheochromocytoma. 12000816

2002
dbSNP: rs74315370
rs74315370
SDHB
0.800 GeneticVariation UNIPROT Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. 11404820

2001