Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913430
rs121913430
EGFR
A 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs138213197
rs138213197
HOXB13
0.030 GeneticVariation BEFREE Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours. 29259341

2017
dbSNP: rs138213197
rs138213197
HOXB13
0.030 GeneticVariation BEFREE Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers. 28186998

2017
dbSNP: rs138213197
rs138213197
HOXB13
0.030 GeneticVariation BEFREE PSA testing, six-core biopsy, genetic counselling and mutation analysis for French Canadian founder mutations in the BRCA1 and BRCA2 genes, histopathological review of tumour tissue from family members, examination of loss of heterozygosity at the BRCA2 gene locus, immunohistochemistry to determine the expression of the ERG nuclear oncoprotein in prostate tumours, genotyping with eight selected risk-associated single nucleotide polymorphisms, Doppler ultrasonography of the leg, CT of the abdomen and pelvis with intravenous and oral contrast, chest CT with intravenous contrast for the assessment of metastatic prostate cancer, genetic testing for the G84E variant in the HOXB13 gene. 23318356

2013
dbSNP: rs137852578
rs137852578
AR
0.020 GeneticVariation BEFREE The gene expression profile of AR-E231G prostate tissue from 12-week-old mice was compared to an equivalent profile from mice expressing the AR-T857A receptor variant (analogous to the AR-T877A variant in LNCaP cells), which do not develop prostate tumors. 22275114

2012
dbSNP: rs486907
rs486907
RNASEL
0.020 GeneticVariation BEFREE A novel gammaretrovirus named xenotropic murine leukemia virus-related virus (XMRV) has been recently identified and found to have a prevalence of 40% in prostate tumor samples from American patients carrying a homozygous R462Q mutation in the RNaseL gene. 19835577

2009
dbSNP: rs486907
rs486907
RNASEL
0.020 GeneticVariation BEFREE Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. 16609730

2006
dbSNP: rs137852578
rs137852578
AR
0.020 GeneticVariation BEFREE Human LNCaP cells, extensively used as a model for androgen-dependent prostate tumor, express the androgen receptor (AR) mutant T877A promiscuously transactivated by estrogens and other ligands, which may further facilitate cancer progression. 12391264

2002
dbSNP: rs148609049
rs148609049
ANO7 ; LOC105373971
0.010 GeneticVariation BEFREE It was found to be an eQTL for ANO7 (Linear model p-values for Finnish patients p = 0.009; Camcap prostate tumor p = 2.53E-06; Stockholm prostate tumor cohort p = 1.53E-13). rs148609049 was not associated with risk, but was related to shorter survival (HR 1.56; 95% CI 1.03-2.36). 30157291

2018
dbSNP: rs368234815
rs368234815
IFNL4
0.010 GeneticVariation BEFREE We show that the <i>IFNL4</i> rs368234815-ΔG allele was significantly associated with IRDS in prostate tumors and overall survival of AA patients. 30012562

2018
dbSNP: rs1057519864
rs1057519864
AR
0.010 GeneticVariation BEFREE CDK4/6i was also effective in prostate tumor models expressing the AR-V7 variant or the AR F876L mutation, both of which are associated with treatment resistance. 28209757

2017
dbSNP: rs1060501201
rs1060501201
TP53
0.010 GeneticVariation BEFREE Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers. 28186998

2017
dbSNP: rs1197734477
rs1197734477
PTEN
0.010 GeneticVariation BEFREE Somatic molecular subtyping of prostate tumors from HOXB13 G84E carriers. 28186998

2017
dbSNP: rs2155222
rs2155222 		0.010 GeneticVariation BEFREE The findings indicate the functionality of the PrCa death-predisposing SNPs rs143975731, rs12277366, rs2155225, and rs2155222 as DGAT2 regulators in prostate tumors.© 2016 Wiley Periodicals, Inc. 27113481

2016
dbSNP: rs1057519971
rs1057519971
SPOP ; LOC107984999
0.010 GeneticVariation BEFREE We sequenced the SPOP gene to identify somatic mutations in 49 AA prostate tumors and identified three missense mutations (p.Y87C, p.F102S, and p.G111E) in five AA prostate tumors (10%) and one synonymous variant (p.I106I) in one tumor. 24994784

2015
dbSNP: rs339331
rs339331
RFX6
0.010 GeneticVariation BEFREE Finally, we observe a significant association between the risk-associated T allele at rs339331 and increased RFX6 mRNA levels in human prostate tumors. 24390282

2014
dbSNP: rs375118292
rs375118292
CUL3
0.010 GeneticVariation BEFREE Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion. 24796539

2014
dbSNP: rs727502792
rs727502792
SPOP
0.010 GeneticVariation BEFREE Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion. 24796539

2014
dbSNP: rs746001963
rs746001963
ERG
0.010 GeneticVariation BEFREE Analysis of the prostate tumor from this individual verified the presence of heterozygous N296I as well as an ERG fusion. 24796539

2014
dbSNP: rs1057519912
rs1057519912
MED12
0.010 GeneticVariation BEFREE So far, the recently reported MED12 p.L1224F mutation could not be validated in our unselected cohort of prostate tumours. 23661306

2013
dbSNP: rs16861209
rs16861209
ADIPOQ
0.010 GeneticVariation BEFREE Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue. 21960694

2011
dbSNP: rs17366568
rs17366568
ADIPOQ ; ADIPOQ-AS1
0.010 GeneticVariation BEFREE Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue. 21960694

2011
dbSNP: rs182052
rs182052
ADIPOQ
0.010 GeneticVariation BEFREE Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue. 21960694

2011
dbSNP: rs266729
rs266729
ADIPOQ
0.010 GeneticVariation BEFREE Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue. 21960694

2011
dbSNP: rs3774261
rs3774261
ADIPOQ ; ADIPOQ-AS1
0.010 GeneticVariation BEFREE Two of the risk SNPs (rs266729 and rs182052) plus four other SNPs (rs16861209, rs17366568, rs3774261, and rs7639352) were also associated with plasma adiponectin levels, and three of these (rs1686109, rs17366568, and rs3774261) were also significantly associated with IR expression in prostate tumor tissue. 21960694

2011