DisGeNET - a database of gene-disease associations

Thyroid Neoplasm, C0040136

Variant: rs112445441 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs112445441

KRAS

0.700

CausalMutation

CLINVAR

Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer.

23406027

2013

dbSNP:

rs112445441

KRAS

0.700

CausalMutation

CLINVAR

Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma.

19773371

2009

dbSNP:

rs112445441

KRAS

0.700

CausalMutation

CLINVAR

Phase II trial of sorafenib in metastatic thyroid cancer.

19255327

2009

dbSNP:

rs112445441

KRAS

0.700

CausalMutation

CLINVAR

Hyperactive Ras in developmental disorders and cancer.

17384584

2007