Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs77709286
rs77709286
RET
G 0.700 GeneticVariation CLINVAR Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. 22025146

2012

dbSNP: rs77709286
rs77709286
RET
G 0.700 GeneticVariation CLINVAR Thyroid cancer cell lines harboring RET/PTC1 (TPC-1), RET M918T (MZ-CRC1) and RET C634W (TT) alterations, as well as TPC-1 xenografts, were treated with JAK inhibitor, AZD1480. 23056499

2012

dbSNP: rs77709286
rs77709286
RET
G 0.700 GeneticVariation CLINVAR The effects of four different tyrosine kinase inhibitors on medullary and papillary thyroid cancer cells. 21470995

2011

dbSNP: rs77709286
rs77709286
RET
G 0.700 GeneticVariation CLINVAR Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer. 20065189

2010