Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE Further studies with larger sample sizes and consideration of gene-environment interactions should be conducted to elucidate the role of <i>IFNG</i> +874 T/A(rs2430561) polymorphism in tuberculosis susceptibility. 28881572

2017

dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE In this study, we investigated a possible association between interleukin-10 (IL-10) -1082A⁄G (rs1800896) and interferon (IFN)-gamma +874T/A (rs2430561) promoter polymorphisms and tuberculosis (TB) in the Azeri population of Iran. 27424131

2016

dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE The IFN-γ polymorphisms, rs1861494, rs2069718, and rs2430561, may confer the risk of TB in Han Taiwanese. 24529854

2015

dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE Previous studies identified the variant IFNG +874A/T (rs2430561) in the first intron of the gene in association with mycobacterial infection, especially tuberculosis and leprosy. 24389160

2014

dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE Given its key role in the control of tuberculosis (TB), in the present article we have investigated a possible association between IFN-γ gene single-nucleotide polymorphism linked to high and low producer phenotypes (IFN-γ [+874T(high) → A(low)]) (rs2430561) and risk development of active TB in Tunisian patients. 21332391

2011

dbSNP: rs2430561
rs2430561
0.060 GeneticVariation BEFREE It was found that genetic variants TG/GG of rs2243115(IL12A) were associated with a decreased risk of TB, with odds ratio (95% confidence interval) of 0.70 (0.49-0.99), whereas variant genotypes AT/TT of rs2430561(IFNG) conferred 82% less risk for treatment failure, with a hazard ratio of 0.18 (95% confidence interval 0.04-0.73). 20544370

2010

dbSNP: rs1861494
rs1861494
0.030 GeneticVariation BEFREE IFNG rs1861494 polymorphism was associated with TB, particularly in the younger and male subgroups. 31310896

2019

dbSNP: rs1861494
rs1861494
0.030 GeneticVariation BEFREE However, our findings indicate that the rs1861494 single nucleotide polymorphism (SNP) could be considered as a biomarker of tuberculosis resistance in the Argentinean population. 29361774

2018

dbSNP: rs1861494
rs1861494
0.030 GeneticVariation BEFREE Three IFN-γ polymorphisms in intron 3, rs1861494 and rs2069718, and rs2430561 in interon 1 were strongly associated with TB. 24529854

2015

dbSNP: rs2069718
rs2069718
0.010 GeneticVariation BEFREE The IFN-γ polymorphisms, rs1861494, rs2069718, and rs2430561, may confer the risk of TB in Han Taiwanese. 24529854

2015