rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Further studies with larger sample sizes and consideration of gene-environment interactions should be conducted to elucidate the role of <i>IFNG</i> +874 T/A(rs2430561) polymorphism in tuberculosis susceptibility.
|
28881572 |
2017 |
rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In this study, we investigated a possible association between interleukin-10 (IL-10) -1082A⁄G (rs1800896) and interferon (IFN)-gamma +874T/A (rs2430561) promoter polymorphisms and tuberculosis (TB) in the Azeri population of Iran.
|
27424131 |
2016 |
rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The IFN-γ polymorphisms, rs1861494, rs2069718, and rs2430561, may confer the risk of TB in Han Taiwanese.
|
24529854 |
2015 |
rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Previous studies identified the variant IFNG +874A/T (rs2430561) in the first intron of the gene in association with mycobacterial infection, especially tuberculosis and leprosy.
|
24389160 |
2014 |
rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Given its key role in the control of tuberculosis (TB), in the present article we have investigated a possible association between IFN-γ gene single-nucleotide polymorphism linked to high and low producer phenotypes (IFN-γ [+874T(high) → A(low)]) (rs2430561) and risk development of active TB in Tunisian patients.
|
21332391 |
2011 |
rs2430561
|
|
|
0.060 |
GeneticVariation |
BEFREE |
It was found that genetic variants TG/GG of rs2243115(IL12A) were associated with a decreased risk of TB, with odds ratio (95% confidence interval) of 0.70 (0.49-0.99), whereas variant genotypes AT/TT of rs2430561(IFNG) conferred 82% less risk for treatment failure, with a hazard ratio of 0.18 (95% confidence interval 0.04-0.73).
|
20544370 |
2010 |
rs1861494
|
|
|
0.030 |
GeneticVariation |
BEFREE |
IFNG rs1861494 polymorphism was associated with TB, particularly in the younger and male subgroups.
|
31310896 |
2019 |
rs1861494
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, our findings indicate that the rs1861494 single nucleotide polymorphism (SNP) could be considered as a biomarker of tuberculosis resistance in the Argentinean population.
|
29361774 |
2018 |
rs1861494
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Three IFN-γ polymorphisms in intron 3, rs1861494 and rs2069718, and rs2430561 in interon 1 were strongly associated with TB.
|
24529854 |
2015 |
rs2069718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The IFN-γ polymorphisms, rs1861494, rs2069718, and rs2430561, may confer the risk of TB in Han Taiwanese.
|
24529854 |
2015 |