Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12252
rs12252
0.040 GeneticVariation BEFREE The IFITM3 allele (rs12252-C) was suggested as a population-based genetic risk factor for severe influenza virus infection by A(H1N1)pdm09. 28842783

2018

dbSNP: rs12252
rs12252
0.040 GeneticVariation BEFREE <i>IFITM3</i> rs12252-C was associated with severe influenza virus infection in several studies, however whether this association is universal to all types of influenza virus or diverse ethnic populations remain controversial. 28713779

2017

dbSNP: rs12252
rs12252
0.040 GeneticVariation BEFREE Our meta-analysis suggests that IFITM3 rs12252 T>C polymorphism is significantly associated with increased risk of severe influenza but not with the chance of initial virus infection. 25778715

2015

dbSNP: rs12252
rs12252
0.040 GeneticVariation BEFREE The SNP rs12252-C allele alters the function of interferon-induced transmembrane protein-3 increasing the disease severity of influenza virus infection in Caucasians, but the allele is rare. 23361009

2013

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE In addition, there was no statistically significant association between MTHFR C677T polymorphism and viral infection, even considering hr-HPV or HPV 16 positivity. 31170928

2019

dbSNP: rs12979860
rs12979860
0.020 GeneticVariation BEFREE In this study, the distribution of IL28B SNPs (rs12979860 and rs12980275) and HLA rs4273729 in rapid virologic response (RVR), complete early virologic response (cEVR) and sustained virologic response (SVR) in HCV Iranian patients with CHC virus infection was assessed. 27714501

2017

dbSNP: rs4804803
rs4804803
0.020 GeneticVariation BEFREE Among significant associations found between virus infections and genetic variants, we report for the first time an association of rs4804803 (CD209) A and G variants with susceptibility to HBV infection and spontaneous clearance (p<0.001, OR=3.53, 95% CI 2.155; 5.908, and p<0.001, OR=7.75, 95% CI 4.646-13.114, respectively). 24797387

2014

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE Using χ square test for the control group, the HPV-negative and HPV-positive patients with cervix lesions, a significant correlation between viral infection and T allele of C677T polymorphism (P = 0.0287) was found. 23444906

2013

dbSNP: rs4804803
rs4804803
0.020 GeneticVariation BEFREE Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. 22061615

2012

dbSNP: rs12979860
rs12979860
0.020 GeneticVariation BEFREE We compared genotypes of the rs12979860 polymorphism, located proximal to the IL28 gene, with serum lipid and apolipoprotein levels in 746 subjects with chronic hepatitis C virus infection, not currently undergoing treatment, using multivariable analysis of variance. 20235331

2010

dbSNP: rs1800562
rs1800562
0.010 GeneticVariation BEFREE Prevalence and characteristics of anti-HCV positivity and chronic hepatitis C virus infection in HFE p.C282Y homozygotes. 31056361

2020

dbSNP: rs7269320
rs7269320
0.010 GeneticVariation BEFREE Relatively weak inducible IFN-β production in HBV infected patients with IPS-1 rs7269320 SNP or wild-type may contribute to chronic virus infection. 30930359

2019

dbSNP: rs12212067
rs12212067
0.010 GeneticVariation BEFREE Thus, enhanced FOXO3 activity such as in the polymorphism rs12212067 may be protective in chronic inflammation such as cancer and cardiovascular disease but disadvantageous to control acute viral infection. 29136142

2018

dbSNP: rs139226823
rs139226823
0.010 GeneticVariation BEFREE We sought to describe the effect on hematopoiesis and immunity of the compound heterozygous R83C/R291Q mutation of IRF8, which is present in a patient with recurrent viral infection, granuloproliferation, and intracerebral calcification. 29128673

2018

dbSNP: rs755850200
rs755850200
VDR
0.010 GeneticVariation BEFREE To date, six major VDR polymorphisms (Cdx, A1012G, FokI, BsmI, ApaI and TaqI) have been studied in the context of viral infection susceptibility. 30092343

2018

dbSNP: rs10774671
rs10774671
0.010 GeneticVariation BEFREE The SS risk allele of rs10774671 has been shown by others to be associated with reduced OAS1 enzymatic activity and ability to clear viral infections, as well as reduced responsiveness to IFN treatment. 28640813

2017

dbSNP: rs11614913
rs11614913
0.010 GeneticVariation BEFREE In addition, we found that rs2292832 and rs11614913 were associated with risk of HBV infection, viral clearance and cirrhosis+HCC, whereas rs2910164 was associated with proneness to HBV infection, and ability to clear the virus. 28685993

2017

dbSNP: rs12980275
rs12980275
0.010 GeneticVariation BEFREE In this study, the distribution of IL28B SNPs (rs12979860 and rs12980275) and HLA rs4273729 in rapid virologic response (RVR), complete early virologic response (cEVR) and sustained virologic response (SVR) in HCV Iranian patients with CHC virus infection was assessed. 27714501

2017

dbSNP: rs1364498756
rs1364498756
0.010 GeneticVariation BEFREE In response to interferon-β, the T387A mutant of STAT2 is much more effective than wild-type STAT2 in mediating the expression of many interferon-stimulated genes, in protecting cells against virus infection, and in inhibiting cell growth. 27852626

2017

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE Inconsistency of reported associations between the tumor necrosis factor-alpha-308 (TNFα-308) polymorphism (rs1800629) and dengue virus infection prompted a meta-analysis, to obtain more precise estimates. 28495402

2017

dbSNP: rs1990760
rs1990760
0.010 GeneticVariation BEFREE The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. 28553952

2017

dbSNP: rs2287622
rs2287622
0.010 GeneticVariation BEFREE A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, China. 28292275

2017

dbSNP: rs4273729
rs4273729
0.010 GeneticVariation BEFREE IL28B genotyping and rs4273729 were performed using the amplification refractory mutation system (ARMS)-PCR and direct sequencing in 190 CHC virus infections, respectively. 27714501

2017

dbSNP: rs10814325
rs10814325
0.010 GeneticVariation BEFREE RECK Gene Promoter rs10814325 Polymorphism in Egyptian Patients with Hepatocellular Carcinoma on Top of Chronic Hepatitis C Viral Infection. 27268601

2016

dbSNP: rs371194629
rs371194629
0.010 GeneticVariation BEFREE Different studies have analyzed the role of rs371194629 in hepatic injury, with either hepatotropic virus infection (i.e., HBV or HCV) or hepatocellular carcinoma (also induced by viral infection). 27706615

2016