rs12252
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The IFITM3 allele (rs12252-C) was suggested as a population-based genetic risk factor for severe influenza virus infection by A(H1N1)pdm09.
|
28842783 |
2018 |
rs12252
|
|
|
0.040 |
GeneticVariation |
BEFREE |
<i>IFITM3</i> rs12252-C was associated with severe influenza virus infection in several studies, however whether this association is universal to all types of influenza virus or diverse ethnic populations remain controversial.
|
28713779 |
2017 |
rs12252
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our meta-analysis suggests that IFITM3 rs12252 T>C polymorphism is significantly associated with increased risk of severe influenza but not with the chance of initial virus infection.
|
25778715 |
2015 |
rs12252
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The SNP rs12252-C allele alters the function of interferon-induced transmembrane protein-3 increasing the disease severity of influenza virus infection in Caucasians, but the allele is rare.
|
23361009 |
2013 |
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In addition, there was no statistically significant association between MTHFR C677T polymorphism and viral infection, even considering hr-HPV or HPV 16 positivity.
|
31170928 |
2019 |
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, the distribution of IL28B SNPs (rs12979860 and rs12980275) and HLA rs4273729 in rapid virologic response (RVR), complete early virologic response (cEVR) and sustained virologic response (SVR) in HCV Iranian patients with CHC virus infection was assessed.
|
27714501 |
2017 |
rs4804803
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Among significant associations found between virus infections and genetic variants, we report for the first time an association of rs4804803 (CD209) A and G variants with susceptibility to HBV infection and spontaneous clearance (p<0.001, OR=3.53, 95% CI 2.155; 5.908, and p<0.001, OR=7.75, 95% CI 4.646-13.114, respectively).
|
24797387 |
2014 |
rs1217691063
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using χ square test for the control group, the HPV-negative and HPV-positive patients with cervix lesions, a significant correlation between viral infection and T allele of C677T polymorphism (P = 0.0287) was found.
|
23444906 |
2013 |
rs4804803
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We compared genotypes of the rs12979860 polymorphism, located proximal to the IL28 gene, with serum lipid and apolipoprotein levels in 746 subjects with chronic hepatitis C virus infection, not currently undergoing treatment, using multivariable analysis of variance.
|
20235331 |
2010 |
rs1800562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Prevalence and characteristics of anti-HCV positivity and chronic hepatitis C virus infection in HFE p.C282Y homozygotes.
|
31056361 |
2020 |
rs7269320
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Relatively weak inducible IFN-β production in HBV infected patients with IPS-1 rs7269320 SNP or wild-type may contribute to chronic virus infection.
|
30930359 |
2019 |
rs12212067
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, enhanced FOXO3 activity such as in the polymorphism rs12212067 may be protective in chronic inflammation such as cancer and cardiovascular disease but disadvantageous to control acute viral infection.
|
29136142 |
2018 |
rs139226823
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We sought to describe the effect on hematopoiesis and immunity of the compound heterozygous R83C/R291Q mutation of IRF8, which is present in a patient with recurrent viral infection, granuloproliferation, and intracerebral calcification.
|
29128673 |
2018 |
rs755850200
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To date, six major VDR polymorphisms (Cdx, A1012G, FokI, BsmI, ApaI and TaqI) have been studied in the context of viral infection susceptibility.
|
30092343 |
2018 |
rs10774671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SS risk allele of rs10774671 has been shown by others to be associated with reduced OAS1 enzymatic activity and ability to clear viral infections, as well as reduced responsiveness to IFN treatment.
|
28640813 |
2017 |
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, we found that rs2292832 and rs11614913 were associated with risk of HBV infection, viral clearance and cirrhosis+HCC, whereas rs2910164 was associated with proneness to HBV infection, and ability to clear the virus.
|
28685993 |
2017 |
rs12980275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, the distribution of IL28B SNPs (rs12979860 and rs12980275) and HLA rs4273729 in rapid virologic response (RVR), complete early virologic response (cEVR) and sustained virologic response (SVR) in HCV Iranian patients with CHC virus infection was assessed.
|
27714501 |
2017 |
rs1364498756
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In response to interferon-β, the T387A mutant of STAT2 is much more effective than wild-type STAT2 in mediating the expression of many interferon-stimulated genes, in protecting cells against virus infection, and in inhibiting cell growth.
|
27852626 |
2017 |
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Inconsistency of reported associations between the tumor necrosis factor-alpha-308 (TNFα-308) polymorphism (rs1800629) and dengue virus infection prompted a meta-analysis, to obtain more precise estimates.
|
28495402 |
2017 |
rs1990760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
|
28553952 |
2017 |
rs2287622
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, China.
|
28292275 |
2017 |
rs4273729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL28B genotyping and rs4273729 were performed using the amplification refractory mutation system (ARMS)-PCR and direct sequencing in 190 CHC virus infections, respectively.
|
27714501 |
2017 |
rs10814325
|
|
|
0.010 |
GeneticVariation |
BEFREE |
RECK Gene Promoter rs10814325 Polymorphism in Egyptian Patients with Hepatocellular Carcinoma on Top of Chronic Hepatitis C Viral Infection.
|
27268601 |
2016 |
rs371194629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Different studies have analyzed the role of rs371194629 in hepatic injury, with either hepatotropic virus infection (i.e., HBV or HCV) or hepatocellular carcinoma (also induced by viral infection).
|
27706615 |
2016 |