| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
A | 0.700 | CausalMutation | CLINVAR | Clinical impact of TP53 alterations in adrenocortical carcinomas. | 22203015 | 2012 |
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|
A | 0.700 | CausalMutation | CLINVAR | Pleomorphic carcinoma of the lung arising in a patient with Li-Fraumeni syndrome: report of a case. | 21626334 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | Early occurrence of lung adenocarcinoma and breast cancer after radiotherapy of a chest wall sarcoma in a patient with a de novo germline mutation in TP53. | 21225465 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | Gastric cancer in individuals with Li-Fraumeni syndrome. | 21552135 | 2011 |
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|
A | 0.700 | CausalMutation | CLINVAR | Recognition of Li Fraumeni syndrome at diagnosis of a locally advanced extremity rhabdomyosarcoma. | 16534790 | 2007 |
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|
A | 0.700 | CausalMutation | CLINVAR | Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome. | 16401470 | 2006 |
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|
A | 0.700 | CausalMutation | CLINVAR | p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition. | 11479205 | 2001 |
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|
A | 0.700 | CausalMutation | CLINVAR | Are there low-penetrance TP53 Alleles? evidence from childhood adrenocortical tumors. | 10486318 | 1999 |
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|
A | 0.700 | CausalMutation | CLINVAR | Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. | 7887414 | 1995 |
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|
A | 0.700 | CausalMutation | CLINVAR | Predominantly tumor-limited expression of a mutant allele in a Japanese family carrying a germline p53 mutation. | 8134126 | 1994 |