Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736100
rs2736100
TERT
G 0.880 GeneticVariation GWASCAT Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma. 27501781

2016
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE These results suggest that the rs2736100T/G polymorphism modulates IL-6 expression and may play a unique role in lung adenocarcinoma. 24420154

2014
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE In conclusion, this meta-analysis demonstrated that TERT rs2736100 polymorphism is a risk factor associated with increased lung cancer susceptibility, particularly for lung adenocarcinoma. 24390616

2014
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE We additionally found an increased risk of non-small cell lung cancer and lung adenocarcinoma strongly associated with rs2736100. 24590268

2014
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE Gene variations rs2736100 and rs2853676 in TERT and rs401681 and rs31489 in CLPTM1L had significant direct associations on lung adenocarcinoma without indirect effects through nicotine dependence. 25233467

2014
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE A recent genome-wide association study of lung cancer among never-smoking females in Asia demonstrated that the rs2736100 polymorphism in the TERT-CLPTM1L locus on chromosome 5p15.33 was strongly and significantly associated with risk of adenocarcinoma of the lung. 23555636

2013
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation GWASDB A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. 22797724

2012
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE For rs2736100, the G variant and the GG genotype were more frequent, whereas the TT genotype was less frequent in patients with lung adenocarcinoma than in controls. 22370939

2012
dbSNP: rs2736100
rs2736100
TERT
G 0.880 GeneticVariation GWASDB Since most women in Asia do not smoke, we conducted a genome-wide association study of lung adenocarcinoma in never-smoking females (584 cases, 585 controls) among Han Chinese in Taiwan and found that the most significant association was for rs2736100 on chromosome 5p15.33 (p = 1.30 x 10(-11)). 20700438

2010
dbSNP: rs2736100
rs2736100
TERT
C 0.880 GeneticVariation GWASCAT The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs2736100
rs2736100
TERT
G 0.880 GeneticVariation GWASCAT Since most women in Asia do not smoke, we conducted a genome-wide association study of lung adenocarcinoma in never-smoking females (584 cases, 585 controls) among Han Chinese in Taiwan and found that the most significant association was for rs2736100 on chromosome 5p15.33 (p = 1.30 x 10(-11)). 20700438

2010
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs2736100
rs2736100
TERT
0.880 GeneticVariation BEFREE Since most women in Asia do not smoke, we conducted a genome-wide association study of lung adenocarcinoma in never-smoking females (584 cases, 585 controls) among Han Chinese in Taiwan and found that the most significant association was for rs2736100 on chromosome 5p15.33 (p = 1.30 x 10(-11)). 20700438

2010
dbSNP: rs2736100
rs2736100
TERT
C 0.880 GeneticVariation GWASDB The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs2736100
rs2736100
TERT
G 0.880 GeneticVariation GWASCAT A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs2736100
rs2736100
TERT
G 0.880 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs10937405
rs10937405
TP63
0.840 GeneticVariation BEFREE When analyzed according to histological type, the effects of rs10937405, and rs4488809 at 3q28 on the risk of lung cancer were significant mostly for lung adenocarcinoma. 24466311

2014
dbSNP: rs10937405
rs10937405
TP63
0.840 GeneticVariation BEFREE Allele comparison showed that the T allele of rs10937405 was associated with a decreased risk of lung adenocarcinoma with an OR of 0.78 (95%CI=0.60-1.01, P=0.059). 24377560

2014
dbSNP: rs10937405
rs10937405
TP63
C 0.840 GeneticVariation GWASDB A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. 22797724

2012
dbSNP: rs10937405
rs10937405
TP63
C 0.840 GeneticVariation GWASCAT A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. 22797724

2012
dbSNP: rs10937405
rs10937405
TP63
0.840 GeneticVariation BEFREE Genetic variation in rs10937405 was associated with risk of lung adenocarcinoma [n = 2,529 cases; p = 7.1 × 10(-8); allelic risk = 0.80, 95% confidence interval (CI) = 0.74-0.87]. 22367405

2012
dbSNP: rs10937405
rs10937405
TP63
C 0.840 GeneticVariation GWASDB The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs10937405
rs10937405
TP63
C 0.840 GeneticVariation GWASCAT The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs10937405
rs10937405
TP63
0.840 GeneticVariation BEFREE The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs401681
rs401681
CLPTM1L
C 0.810 GeneticVariation GWASCAT Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 31326317

2019