rs6547741
|
|
G |
0.710 |
GeneticVariation |
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
rs6547741
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
rs10462706
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
rs10851478
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs1229984
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs1453414
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs1800628
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs2398180
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs3129780
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs3828805
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs77452476
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs79767424
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
rs8181047
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
rs928674
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Pooled results indicated that neither C677T</span> nor A1298C polymorphism was associated with oral cancer susceptibility.
|
28138253 |
2017 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The goals of this study were to evaluate the association of three genotypic polymorphism (MTHFR C677T, MTHFR A1298C and CBS 844ins68) and oral cancer risk in southeastern Brazilians and evaluate the interactions between polymorphisms and clinical histopathological parameters.
|
26749456 |
2016 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The best two-factor based G×G interaction of ora</span>l cancer included the XRCC1 rs1799782 and XRCC2 rs2040639 [OR=3.13, 95% CI=1.66-6.13].
|
25831063 |
2015 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid).
|
24102947 |
2014 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These results suggest that MTHFR C677T polymorphism may play a role in oral cancer carcinogenesis in Asian population and heavy drinkers.
|
24488626 |
2014 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The meta-analysis results suggest that the XRCC1 Arg399Gln and Arg280His polymorphisms are probably not associated with the risk of HNC, but the XRCC1 Arg194Trp polymorphism was associated with increased risk of HNC in the subgroup analysis of studies adjusted for smoking and alcohol and with increased risk of oral cancer in the stratified analyses based on cancer site.
|
24497981 |
2014 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid).
|
24102947 |
2014 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Subgroup analysis by ethnicity suggested that there was an obvious association between XRCC1 Arg194Trp polymorphism and ora</span>l cancer</span> risk in Asians under three genetic models.
|
23681796 |
2013 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Subgroup analyses according to ethnicity, tumor site, publication year, genotyping method also detected no significant association in any subgroup, except that oral cancer was associated with Arg194Trp variant in recessive model.
|
24086310 |
2013 |
rs1799782
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the relationship between the presence of allelic variants Arg194Trp (rs:1799782) and Arg399Gln (rs: 25487) of XRCC1 gene and Thr241Met (rs: 861539) of XRCC3 gene and susceptibility to oral cancer.
|
22775506 |
2013 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Here we observed MTHFR C677T to influence oral cancer susceptibility, while A1298C polymorphism associated with patient prognosis.
|
20923444 |
2011 |