Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6547741
rs6547741
G 0.710 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

dbSNP: rs6547741
rs6547741
0.710 GeneticVariation BEFREE Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

dbSNP: rs10462706
rs10462706
C 0.700 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

dbSNP: rs10851478
rs10851478
G 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs1229984
rs1229984
G 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs1453414
rs1453414
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs1800628
rs1800628
A 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs2398180
rs2398180
T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs3129780
rs3129780
A 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs3828805
rs3828805
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs77452476
rs77452476
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs79767424
rs79767424
C 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. 27749845

2016

dbSNP: rs8181047
rs8181047
A 0.700 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

dbSNP: rs928674
rs928674
G 0.700 GeneticVariation GWASCAT Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845

2016

dbSNP: rs1217691063
rs1217691063
0.080 GeneticVariation BEFREE Pooled results indicated that neither C677T</span> nor A1298C polymorphism was associated with oral cancer susceptibility. 28138253

2017

dbSNP: rs1217691063
rs1217691063
0.080 GeneticVariation BEFREE The goals of this study were to evaluate the association of three genotypic polymorphism (MTHFR C677T, MTHFR A1298C and CBS 844ins68) and oral cancer risk in southeastern Brazilians and evaluate the interactions between polymorphisms and clinical histopathological parameters. 26749456

2016

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE The best two-factor based G×G interaction of ora</span>l cancer included the XRCC1 rs1799782 and XRCC2 rs2040639 [OR=3.13, 95% CI=1.66-6.13]. 25831063

2015

dbSNP: rs1217691063
rs1217691063
0.080 GeneticVariation BEFREE Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid). 24102947

2014

dbSNP: rs1217691063
rs1217691063
0.080 GeneticVariation BEFREE These results suggest that MTHFR C677T polymorphism may play a role in oral cancer carcinogenesis in Asian population and heavy drinkers. 24488626

2014

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE The meta-analysis results suggest that the XRCC1 Arg399Gln and Arg280His polymorphisms are probably not associated with the risk of HNC, but the XRCC1 Arg194Trp polymorphism was associated with increased risk of HNC in the subgroup analysis of studies adjusted for smoking and alcohol and with increased risk of oral cancer in the stratified analyses based on cancer site. 24497981

2014

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid). 24102947

2014

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE Subgroup analysis by ethnicity suggested that there was an obvious association between XRCC1 Arg194Trp polymorphism and ora</span>l cancer</span> risk in Asians under three genetic models. 23681796

2013

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE Subgroup analyses according to ethnicity, tumor site, publication year, genotyping method also detected no significant association in any subgroup, except that oral cancer was associated with Arg194Trp variant in recessive model. 24086310

2013

dbSNP: rs1799782
rs1799782
0.080 GeneticVariation BEFREE The aim of this study was to investigate the relationship between the presence of allelic variants Arg194Trp (rs:1799782) and Arg399Gln (rs: 25487) of XRCC1 gene and Thr241Met (rs: 861539) of XRCC3 gene and susceptibility to oral cancer. 22775506

2013

dbSNP: rs1217691063
rs1217691063
0.080 GeneticVariation BEFREE Here we observed MTHFR C677T to influence oral cancer susceptibility, while A1298C polymorphism associated with patient prognosis. 20923444

2011