rs3769839
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
|
28779025 |
2018 |
rs7731017
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
|
28779025 |
2018 |
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Levels of ISGs and IFNL2/3 mRNAs were lower in IFNL3 rs12979860 CC patients compared with non-CC patients, and in treatment responders, compared with nonresponders.
|
26020282 |
2016 |
rs12979860
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Cirrhosis and rapid virological response to peginterferon plus ribavirin determine treatment outcome in HCV-1 IL28B rs12979860 CC patients.
|
23936821 |
2013 |
rs104886003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next-generation sequencing detected mutations at p.Q61H (c.183A>C) of KRAS and p.E545K (c.1633G>A) of PIK3CA, keeping in line with similarity to conventional cholangiocarcinoma.
|
30591492 |
2019 |
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BRAF inhibitors showed activity in BRAF V600E mutated cholangiocarcinomas and pancreatic carcinomas in non-first line settings.
|
31221175 |
2019 |
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
BRAF inhibitors showed activity in BRAF V600E mutated cholangiocarcinomas and pancreatic carcinomas in non-first line settings.
|
31221175 |
2019 |
rs17851045
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next-generation sequencing detected mutations at p.Q61H (c.183A>C) of KRAS and p.E545K (c.1633G>A) of PIK3CA, keeping in line with similarity to conventional cholangiocarcinoma.
|
30591492 |
2019 |
rs17851045
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next-generation sequencing detected mutations at p.Q61H (c.183A>C) of KRAS and p.E545K (c.1633G>A) of PIK3CA, keeping in line with similarity to conventional cholangiocarcinoma.
|
30591492 |
2019 |
rs2072671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For CDA rs2072671 (A>C), AC and CC patients had a lower risk of neutropenia than AA patients (P=0.01, hazard ratio: 0.61, 95% confidence interval: 0.41-0.89).
|
30889042 |
2019 |
rs3024270
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, decreased risk of invasive bladder cancer was found in carrying rs3024270 CC patients.
|
29595036 |
2019 |
rs4938723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MiR-34b/c rs4938723 was associated with ESCC TNM staging, differentiation degree, and lymph node metastasis (LNM) for ES CC patients (all P < 0.05).
|
29270777 |
2019 |
rs761937143
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next-generation sequencing detected mutations at p.Q61H (c.183A>C) of KRAS and p.E545K (c.1633G>A) of PIK3CA, keeping in line with similarity to conventional cholangiocarcinoma.
|
30591492 |
2019 |
rs889312
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analysis showed that MAP3K1 rs889312 AC/CC significantly reduced OS of patients with tumors smaller than or equal to 5 cm in size (HR, 3.706; 95% CI: 1.329-10.335, <i>p</i>=0.012), poorly differentiated tumors (HR, 3.002; 95% CI: 1.076-8.377, <i>p</i>=0.036) and intestinal tumors (HR, 4.780; 95% CI: 1.138-20.073, <i>p</i>=0.033).
|
31686841 |
2019 |
rs11635252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant decrease was identified in the total cholesterol (TC), triglyceride (TG), and weight in those with CC phenotype compared with those with CT phenotype among the cases with rs11635252 (P < .05).CRTC3 polymorphism was associated with the onset of acute coronary syndrome in Han Chinese patients, which may be related to the imbalance of the lipid metabolism.
|
29979427 |
2018 |
rs2106261
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, neutrophil/lymphocyte (N/L) ratio, C-reactive protein (CRP), and interleukin-6 (IL-6) expression levels were lower in PAF patients with the ZFHX3 SNP rs2106261 minor allele (TT+TC) than in CC patients (N/L ratio: CC 2.22 ± 0.08, TT+TC 1.98 ± 0.06, p = 0.018; CRP: CC 0.103 ± 0.009 mg/dl, TT+TC 0.076 ±0.007 mg/dl, p = 0.016; IL-6: CC 60.3 ± 3.0 pg/ml, TT+TC 52.8 ± 2.3 pg/ml, p = 0.04).
|
30180182 |
2018 |
rs2266788
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, homozygous risk allele of rs2266788 (CC) significantly associated with risk of MI and UA in patients of chronic stable angina (CSA) patients.
|
29309886 |
2018 |
rs7903146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs7903146 C>T polymorphism appeared to modulate the risk of MACE: 5-year prevalence was 0.8% in CC patients, 7.2% in CT patients and 9.7% in TT patients (P<.001).
|
28299838 |
2017 |
rs9679162
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the G<i>ALNT14</i>-rs9679162 'TT' genotype was associated with perineural invasion and lymph node metastasis, as well as unfavorable overall survival in patients with resected cholangiocarcinoma.
|
28588705 |
2017 |
rs2289278
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In children sensitized to certain allergens, a genetic predisposition (rs2289278 genotype CC) significantly increased the risk of AD.
|
26712523 |
2016 |
rs5275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Differentiation of the type 1 EC is significantly and independently influenced by rs5275 polymorphism. rs5275 CC patients have a lower risk to present a G2-G3 EC.
|
25900875 |
2015 |
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C3435T genotype was an independent predictive factor of good response in breast (response >50 %, i.e., Sataloff T-A and T-B): OR: 4.6 (95 % CI: 1.3-16.1), p = 0.015, for TT patients versus CT and CC patients.
|
23666532 |
2013 |
rs1799782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped five non-synonymous single-nucleotide polymorphisms of three genes, including the human homolog of the 8-oxoguanine glycosylase 1 Ser326Cys, X-ray repair cross-complementing protein 1 Arg194Trp, Arg280His and Arg399Gln and poly (adenosine diphosphate ribose) polymerase 1 Val762Ala in 87-94 matched case-control pairs, and examined relations between those polymorphisms and the risk of cholangiocarcinoma.
|
24049014 |
2013 |
rs25487
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped five non-synonymous single-nucleotide polymorphisms of three genes, including the human homolog of the 8-oxoguanine glycosylase 1 Ser326Cys, X-ray repair cross-complementing protein 1 Arg194Trp, Arg280His and Arg399Gln and poly (adenosine diphosphate ribose) polymerase 1 Val762Ala in 87-94 matched case-control pairs, and examined relations between those polymorphisms and the risk of cholangiocarcinoma.
|
24049014 |
2013 |
rs25489
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped five non-synonymous single-nucleotide polymorphisms of three genes, including the human homolog of the 8-oxoguanine glycosylase 1 Ser326Cys, X-ray repair cross-complementing protein 1 Arg194Trp, Arg280His and Arg399Gln and poly (adenosine diphosphate ribose) polymerase 1 Val762Ala in 87-94 matched case-control pairs, and examined relations between those polymorphisms and the risk of cholangiocarcinoma.
|
24049014 |
2013 |