| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.030 | GeneticVariation | BEFREE | We analysed the COMT Val158Met polymorphism in 50 patients with chronic schizophrenia randomly allocated to two treatment conditions for 3 months: standard rehabilitation treatment (SRT) alone and SRT plus specific cognitive exercise of impaired functions. | 17383818 | 2007 |
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0.030 | GeneticVariation | BEFREE | The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia. | 16330500 | 2006 |
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0.030 | GeneticVariation | BEFREE | We examined the effects of the catechol-O-methyltransferase Val(158)Met polymorphism in 58 individuals with chronic schizophrenia who completed a battery of 15 neurocognitive tests, which were reduced to four reliable neurocognitive domain scores. | 12372660 | 2002 |
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0.010 | GeneticVariation | BEFREE | NRG3 rs10748842 may not confer susceptibility to schizophrenia, but may be more closely associated with cognitive deficit, especially attention performance in chronic schizophrenia. | 31753594 | 2020 |
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0.010 | GeneticVariation | BEFREE | Both genotypic distribution and allelic frequency of rs2296225 polymorphism were significantly different between the chronic schizophrenia subjects and controls. | 26421900 | 2015 |
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0.010 | GeneticVariation | BEFREE | This study examines whether the TCF4 rs2958182 polymorphism influences cognitive functions in chronic schizophrenia and controls. | 26343600 | 2015 |
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0.010 | GeneticVariation | BEFREE | We also did not reveal significant associations of the genotypes (OR = 0.82; 95% CI: 0.66, 1.02; P = 0.075) and alleles (OR = 0.90; 95% CI: 0.76, 1.06; P = 0.215) with the risk of TD in schizophrenia.The decreased MnSOD activity may be associated with the risk of chronic schizophrenia in Chinese population, while MnSOD Ala-9Val polymorphism may not play a significant role in the development of schizophrenia and TD. | 26356721 | 2015 |
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0.010 | GeneticVariation | BEFREE | All three polymorphisms as well as an additional polymorphism (rs7566605) were genotyped in 154 patients who underwent treatment for chronic schizophrenia with one of four antipsychotics (clozapine, olanzapine, haloperidol or risperidone). | 20373477 | 2010 |
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0.010 | GeneticVariation | BEFREE | We tested for association between rs6994992 and chronic schizophrenia by genotyping 738 cases from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) and 733 matched controls. | 18286587 | 2008 |