Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD. 29386252

2018

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies. 28349240

2017

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations. 28374168

2017

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Carney triad can be (rarely) associated with germline succinate dehydrogenase defects. 26173966

2016

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. 25683602

2015

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma. 25371406

2015

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Contiguous bilateral head and neck paragangliomas in a carrier of the SDHB germline mutation. 21820839

2012

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. 19802898

2010

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Denaturing high performance liquid chromatography detection of SDHB, SDHD, and VHL germline mutations in pheochromocytoma. 19215943

2009

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Rationale and evidence for sunitinib in the treatment of malignant paraganglioma/pheochromocytoma. 19001511

2009

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Clinical presentations, biochemical phenotypes, and genotype-phenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas. 17200167

2007

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Gastrointestinal stromal tumour in succinate dehydrogenase subunit B mutation-associated familial phaeochromocytoma/paraganglioma. 16916404

2006

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing. 16912137

2006

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. 16317055

2006

dbSNP: rs786201095
rs786201095
C 0.700 CausalMutation CLINVAR Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. 15987702

2005