Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
0.720 GeneticVariation BEFREE This study aimed to evaluate the association of AMD with ApoE gene polymorphism variants (rs7412 and rs429358). 29851526

2018

dbSNP: rs429358
rs429358
0.720 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016

dbSNP: rs429358
rs429358
0.720 GeneticVariation BEFREE In this study, we investigated the association between ApoE C112R/R158C single nucleotide polymorphisms (which determine the E2, E3, and E4 isoforms) and age-related macular degeneration (AMD), and the mechanism underlying the association. 16823865

2006

dbSNP: rs7412
rs7412
0.010 GeneticVariation BEFREE This study aimed to evaluate the association of AMD with ApoE gene polymorphism variants (rs7412 and rs429358). 29851526

2018

dbSNP: rs405509
rs405509
0.010 GeneticVariation BEFREE This would also imply that genotyping of the core epsilon-haplotypes alone is not sufficient to estimate AMD risk, but that determination of extended haplotype combinations, including the functional promoter SNP rs405509, is required instead. 19384966

2009

dbSNP: rs11542041
rs11542041
0.010 GeneticVariation BEFREE In this study, we investigated the association between ApoE C112R/R158C single nucleotide polymorphisms (which determine the E2, E3, and E4 isoforms) and age-related macular degeneration (AMD), and the mechanism underlying the association. 16823865

2006