Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10490924
rs10490924
0.900 GeneticVariation GWASCAT Genome-wide association study of neovascular age-related macular degeneration in the Thai population. 28703135

2018

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Association of risk genotypes of ARMS2/LOC387715 A69S and CFH Y402H with age-related macular degeneration with and without reticular pseudodrusen: a meta-analysis. 28593728

2018

dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation BEFREE Association of risk genotypes of ARMS2/LOC387715 A69S and CFH Y402H with age-related macular degeneration with and without reticular pseudodrusen: a meta-analysis. 28593728

2018

dbSNP: rs11200638
rs11200638
0.900 GeneticVariation GWASCAT Genome-wide association study of neovascular age-related macular degeneration in the Thai population. 28703135

2018

dbSNP: rs11200638
rs11200638
0.900 GeneticVariation BEFREE Association of HTRA1 rs11200638 with age-related macular degeneration (AMD) in Brazilian patients. 28846052

2018

dbSNP: rs2230199
rs2230199
C3
0.900 GeneticVariation GWASCAT Genome-wide analysis of disease progression in age-related macular degeneration. 29346644

2018

dbSNP: rs800292
rs800292
CFH
0.900 GeneticVariation BEFREE To pool the results of published data regarding association of ARMS2/LOC387715 A69S, CFH Y402H and CFH I62V genotypes with age-related macular degeneration (AMD) with and without reticular pseudodrusen (RPD). 28593728

2018

dbSNP: rs800292
rs800292
CFH
0.900 GeneticVariation GWASCAT Genome-wide association study of neovascular age-related macular degeneration in the Thai population. 28703135

2018

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Association of combined cigarette smoking and ARMS2/LOC387715 A69S polymorphisms with age-related macular degeneration: A meta-analysis. 28095100

2017

dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation BEFREE Evaluation of CC-cytokine ligand 2 and complementary factor H Y402H polymorphisms and their interactional association with age-related macular degeneration. 27316788

2017

dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation BEFREE To determine the joint effect of complement component 3(C3 R102G) with CC-cytokine ligand2 (CCL2-2518) or complement factor H (CFH) Y402H polymorphisms on advanced age-related macular degeneration (AMD). 28095095

2017

dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation BEFREE CFH Y402H and VEGF Polymorphisms and Anti-VEGF Treatment Response in Exudative Age-Related Macular Degeneration. 27404493

2017

dbSNP: rs1061170
rs1061170
CFH
0.900 GeneticVariation BEFREE Association of the polymorphism Y402H in the CFH gene with response to anti-VEGF treatment in age-related macular degeneration: a systematic review and meta-analysis. 27151934

2017

dbSNP: rs11200638
rs11200638
0.900 GeneticVariation BEFREE Rs12153855C and rs9391734A alleles could further increase the susceptibility to AMD in subjects with rs800292, rs11200638 and rs429608 risk alleles. 26861912

2017

dbSNP: rs11200638
rs11200638
0.900 GeneticVariation BEFREE Association between polymorphism rs11200638 in the HTRA1 gene and the response to anti-VEGF treatment of exudative AMD: a meta-analysis. 28637435

2017

dbSNP: rs2230199
rs2230199
C3
0.900 GeneticVariation BEFREE To determine the joint effect of complement component 3(C3 R102G) with CC-cytokine ligand2 (CCL2-2518) or complement factor H (CFH) Y402H polymorphisms on advanced age-related macular degeneration (AMD). 28095095

2017

dbSNP: rs800292
rs800292
CFH
0.900 GeneticVariation BEFREE Rs12153855C and rs9391734A alleles could further increase the susceptibility to AMD in subjects with rs800292, rs11200638 and rs429608 risk alleles. 26861912

2017

dbSNP: rs800292
rs800292
CFH
0.900 GeneticVariation BEFREE Association of ARMS2/LOC387715 A69S, CFH Y402H, and CFH I62V polymorphisms with retinal angiomatous proliferation compared with typical age-related macular degeneration: a meta-analysis. 28005184

2017

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE The risk alleles C in CFH rs1061170 (p < 0.0001, Pearson chi-square) and T in ARMS2 rs10490924 (p < 0.0001), as well as smoking (p < 0.0001), were more prevalent in AMD patients compared with controls. 26154559

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Association of LOC387715/ARMS2 (rs10490924) Gene Polymorphism with Age-Related Macular Degeneration in the Brazilian Population. 24372405

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Female sex and the presence of both risk alleles of CFH-rs1061170 or ARMS2-rs10490924 were independently associated with early AMD incidence, whereas current smoking and presence of ≥1 risk allele of CFH-rs1061170 or ARMS2-rs10490924 were associated with late AMD incidence. 26383995

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Patients with GA were significantly older, with a higher prevalence of reticular pseudodrusen, bilateral involvement of advanced AMD and T-allele frequency of ARMS2 A69S compared with those with typical AMD and PCV; although there were no differences in the genetic and clinical characteristics among patients with GA and RAP. 26918864

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Their genetic susceptibility to AMD was significantly lower than that of neovascular AMD; ARMS2 rs10490924 (p = 0.029), CFH rs800292 (p = 0.013) and genetic risk score calculated from 11 AMD susceptibility genes (p = 3.8 × 10(-3)). 26542071

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Risk alleles of three SNPs, rs1061170 (CFH), rs1410996 (CFH), and rs10490924 (ARMS2) were found to be significantly associated with the AMD case/control status as defined by the algorithm. 26255974

2016

dbSNP: rs10490924
rs10490924
0.900 GeneticVariation BEFREE Genetic risk was based on Y402H in complement factor H (CFH) and A69S in age-related maculopathy susceptibility locus 2 (ARMS2). 26354764

2016