rs6918679
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of treatment response to venlafaxine XR in generalized anxiety disorder.
|
28437668 |
2017 |
rs6265
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The present study showed that carrying the Met allele confers increased risk for the presence of generalized anxiety disorder (χ = 4.7, P = .03; OR (95%) 1.96 (1.05-3.56)) when patients with generalized anxiety disorder were compared with the comparison group.Our results provide evidence of an association between the Val66Met polymorphism of the BDNF gene and generalized anxiety disorder in a Mexican population.
|
30882674 |
2019 |
rs759834365
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The present study showed that carrying the Met allele confers increased risk for the presence of generalized anxiety disorder (χ = 4.7, P = .03; OR (95%) 1.96 (1.05-3.56)) when patients with generalized anxiety disorder were compared with the comparison group.Our results provide evidence of an association between the Val66Met polymorphism of the BDNF gene and generalized anxiety disorder in a Mexican population.
|
30882674 |
2019 |
rs6265
|
|
|
0.050 |
GeneticVariation |
BEFREE |
No significant difference was found in the BDNF Val66Met polymorphism between patients with GAD and healthy controls, nor was this polymorphism significantly associated with antidepressant drug efficacy for GAD.
|
29446659 |
2018 |
rs759834365
|
|
|
0.050 |
GeneticVariation |
BEFREE |
No significant difference was found in the BDNF Val66Met polymorphism between patients with GAD and healthy controls, nor was this polymorphism significantly associated with antidepressant drug efficacy for GAD.
|
29446659 |
2018 |
rs6265
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.
|
26110341 |
2015 |
rs6265
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Val66Met variation was not associated with OCD or GAD.
|
26209750 |
2015 |
rs759834365
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Val66Met variation was not associated with OCD or GAD.
|
26209750 |
2015 |
rs759834365
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Met allele of BDNF Val66Met polymorphism is associated with increased BDNF levels in generalized anxiety disorder.
|
26110341 |
2015 |
rs6265
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We did not find a significant association between rs6265 and antidepressant treatment response in our GAD population.
|
21889574 |
2011 |
rs759834365
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Association analysis between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and treatment response to venlafaxine XR in generalized anxiety disorder.
|
21889574 |
2011 |
rs4680
|
|
|
0.020 |
GeneticVariation |
BEFREE |
COMT rs4680 polymorphism was genotyped in 1,655 Han Chinese adults (1,142 healthy subjects and 513 patients with GAD; age: 20-65).
|
30954919 |
2019 |
rs4606
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Logistic regressions adjusted for sex and age revealed that rs4606 interacted with total childhood adversity in predicting each diagnostic outcome except for panic disorder and generalized anxiety disorder, uncorrected and corrected for multiple testing (odds ratio [OR] = 1.06-1.16).
|
30107643 |
2018 |
rs25531
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Utilizing a triallelic assay (5-HTTLPR and rs25531) to assess genetic variation linked with altered serotonin signaling, this fMRI study investigated genetic influences on amygdala and anterior insula activity in 50 generalized anxiety disorder patients, 26 of whom also met DSM-IV criteria for social anxiety disorder and/or major depressive disorder, and 39 healthy comparison subjects.
|
25675343 |
2015 |
rs25531
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined a possible interaction between the serotonin transporter gene (SLC6A4) 5-HTTLPR/rs25531 haplotype and the serotonin 2A receptor gene (HTR2A) single-nucleotide polymorphism (SNP) rs7997012 in antidepressant treatment outcome in GAD.
|
22907732 |
2013 |
rs7997012
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We examined a possible interaction between the serotonin transporter gene (SLC6A4) 5-HTTLPR/rs25531 haplotype and the serotonin 2A receptor gene (HTR2A) single-nucleotide polymorphism (SNP) rs7997012 in antidepressant treatment outcome in GAD.
|
22907732 |
2013 |
rs7997012
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested the hypothesis that the genetic polymorphism rs7997012 in the HTR2A gene predicts treatment outcome in GAD patients treated with venlafaxine XR.
|
22006095 |
2013 |
rs4680
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Furthermore, we show a slight dominant effect of the A-allele with the CGI-I measure in the European American population indicating a possible pharmacogenetic role of rs4680 in antidepressant treatment outcome in GAD.
|
22417933 |
2012 |
rs4606
|
|
|
0.020 |
GeneticVariation |
BEFREE |
RGS2 SNP rs4606 was significantly associated with GAD in this sample.
|
18833580 |
2009 |
rs324981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of NPSR1 rs324981 polymorphism and treatment response to antidepressants in Chinese Han population with generalized anxiety disorder.
|
30190127 |
2018 |
rs11568817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In women with ADHD, the same rs11568817 was associated with generalized anxiety disorder (P<sub>corr</sub> = 0.031).
|
28923721 |
2017 |
rs78602344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One genotyped SNP (rs78602344) intronic to thrombospondin 2 (THBS2) was nominally associated (P = 5.28 × 10<sup>-8</sup> ) in the primary analysis adjusting for psychiatric medication use and significantly associated with the GAD symptoms score in the analysis excluding medication users (P = 4.18 × 10<sup>-8</sup> ).
|
27159506 |
2017 |
rs1043307
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our study, the PSMD9 gene SNPs rs74421874, rs3825172, and rs1043307/rs2514259 result in linkage to generalized anxiety disorder.
|
24648162 |
2014 |
rs14259
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 200 Italians families were tested for the PSMD9 T2D risk SNPs rs74421874 (IVS3 + nt460 G>A), rs3825172 (IVS3 +nt437 T>C) and for the T2D risk and anti-depressant response SNP rs1043307/rs2514259 (E197G A>G) for evidence of linkage with generalized anxiety disorder.
|
24648162 |
2014 |
rs2514259
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In our study, the PSMD9 gene SNPs rs74421874, rs3825172, and rs1043307/rs2514259 result in linkage to generalized anxiety disorder.
|
24648162 |
2014 |