Two polymorphisms (Lys109Arg, Gln223Arg) in the extracellular domain of the leptin receptor predicted the conversion to type 2 diabetes in high-risk individuals with IGT.
In premenopausal women with IGT</span> (n = 65), associations were found with Lys(109)Argand Lys(656)Asn for overall glucose response to the glucose load.