Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE Critical role of methionine-722 in the stimulation of human brain G-proteins and neurotoxicity induced by London familial Alzheimer's disease (FAD) mutated V717G-APP(714-723). 17101228

2007

dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE In familial Alzheimer's disease (FAD), three missense mutations, V642I, V642F and V642G, that co-segregate with the disease phenotype have been discovered in the 695 amino acid form of the amyloid precursor protein APP. 9305632

1997

dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE In dominantly inherited familial Alzheimer's disease (FAD), point mutations V6421, V642F and V642G have been discovered in APP695. 8599933

1996

dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE Seven at risk members of a familial Alzheimer's disease pedigree associated with the amyloid precursor protein 717 valine to glycine mutation underwent serial MR scanning and neuropsychological assessments over 3 years. 9010004

1996

dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine-->glycine). 8461968

1993

dbSNP: rs63749964
rs63749964
APP
0.060 GeneticVariation BEFREE Tau pathology in a case of familial Alzheimer's disease with a valine to glycine mutation at position 717 in the amyloid precursor protein. 1465214

1992