Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs387907272
rs387907272
0.050 GeneticVariation BEFREE Clinicopathologic correlates of <i>MYD88</i> L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma. 31184237

2019

dbSNP: rs387907272
rs387907272
0.050 GeneticVariation BEFREE In a cohort of 23 PCNSL patients, L265P MYD88 mutations were examined in tumor-free BM mononuclear cells (MNC) in which the PCNSL tumors had L265P MYD88 mutations. 30353605

2019

dbSNP: rs387907272
rs387907272
0.050 GeneticVariation BEFREE The MyD88 L265P mutation predicted a poor prognosis in elderly PCNSL patients. 29258950

2018

dbSNP: rs387907272
rs387907272
0.050 GeneticVariation BEFREE To investigate how sensitively the MYD88 L265P mutation can be identified in cell-free DNA from PCNSL patients, we carried out droplet digital PCR (ddPCR) and targeted deep sequencing (TDS) in 14 consecutive PCNSL patients from whom paired tumor-derived DNA and cell-free DNA was available at diagnosis. 29151258

2018

dbSNP: rs387907272
rs387907272
0.050 GeneticVariation BEFREE Nine of these samples tested positive for MYD88 p.(L265P) (8 LPL and 1 PCNSL). 29210102

2018

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE Methotrexate elimination and toxicity: MTHFR 677C>T polymorphism in patients with primary CNS lymphoma treated with high-dose methotrexate. 27781293

2017

dbSNP: rs1801131
rs1801131
0.010 GeneticVariation BEFREE Furthermore, for the methylenetetrahydrofolate reductase (MTHFR) c.1298A > C (E429A) polymorphism the mutated C-allele was found more frequently among PCNSL patients than among population controls (P = 0.026; OR = 1.57; 1.05-2.34). 20237949

2010

dbSNP: rs1805087
rs1805087
MTR
0.010 GeneticVariation BEFREE The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma. 15138479

2004