Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4680
rs4680
0.020 GeneticVariation BEFREE The objective of this study was to evaluate the influence of Val158Met on FER during manic and depressive episodes in BD patients and in healthy controls. 22222175

2012

dbSNP: rs4680
rs4680
0.020 GeneticVariation BEFREE We observed a significant association between homozygosis for the rs4680 COMT low-activity variant and a reduced recurrence of manic, but not depressive, episodes during the course of the illness. 21397335

2011

dbSNP: rs2227283
rs2227283
0.010 GeneticVariation BEFREE Correlation between GRIK2 rs6922753, rs2227283 polymorphism and aggressive behaviors with Bipolar Mania in the Chinese Han population. 31631587

2019

dbSNP: rs6922753
rs6922753
0.010 GeneticVariation BEFREE This study aims to verify whether the rs6922753 and rs2227283 polymorphisms of the GRIK2 gene are associated with both aggressive behavior and bipolar mania in the Chinese Han population. 31631587

2019

dbSNP: rs12630592
rs12630592
0.010 GeneticVariation BEFREE In mood disorder patients, the level of mania (in both acute and stabilized periods) and depression in stabilized periods was positively associated with GSK3B rs12630592 T only in FXR1 rs496250 A-allele carriers (Bonferroni-corrected interaction p=0.024, 0.052 and 0.017 respectively). 28242499

2017

dbSNP: rs496250
rs496250
0.010 GeneticVariation BEFREE In mood disorder patients, the level of mania (in both acute and stabilized periods) and depression in stabilized periods was positively associated with GSK3B rs12630592 T only in FXR1 rs496250 A-allele carriers (Bonferroni-corrected interaction p=0.024, 0.052 and 0.017 respectively). 28242499

2017

dbSNP: rs165599
rs165599
0.010 GeneticVariation BEFREE Allele G from COMT SNPs rs4680 and rs165599 may represent reliable state-dependent predictors of global CD during manic and mixed episodes in BD. 22713126

2012

dbSNP: rs6265
rs6265
0.010 GeneticVariation BEFREE Sixty-six subjects with BD (41 in manic and 25 in depressive episodes) and 78 healthy volunteers were genotyped for BDNF Val(66)Met and tested for creativity using the Barrow Welsh Art Scale (BWAS) and neuropsychological tests. 22484201

2012

dbSNP: rs759834365
rs759834365
0.010 GeneticVariation BEFREE Sixty-six subjects with BD (41 in manic and 25 in depressive episodes) and 78 healthy volunteers were genotyped for BDNF Val(66)Met and tested for creativity using the Barrow Welsh Art Scale (BWAS) and neuropsychological tests. 22484201

2012