Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs869025212
rs869025212
BAP1
A 0.700 CausalMutation CLINVAR Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma Patients. 25687217

2015
dbSNP: rs17338032
rs17338032
CRTAM
0.700 GeneticVariation GWASDB A genome-wide association study for malignant mesothelioma risk. 23827383

2013
dbSNP: rs121907906
rs121907906
WT1
A 0.700 CausalMutation CLINVAR

dbSNP: rs1049305
rs1049305
AQP1
0.010 GeneticVariation BEFREE Results AQP1 rs1049305 polymorphism was significantly associated with MM risk in dominant model adjusted for gender and age (OR = 0.60, 95% CI = 0.37-0.96, Padj = 0.033). 30840592

2019
dbSNP: rs11615
rs11615
ERCC1
0.010 GeneticVariation BEFREE Interaction between ERCC1 rs11615</span> and asbestos exposure significantly influenced MM risk (OR = 3.61; 95% CI = 1.12-11.66; p = 0.032). 30893058

2019
dbSNP: rs3212986
rs3212986
ERCC1 ; CD3EAP
0.010 GeneticVariation BEFREE Results ERCC1 rs3212986 polymorphism was significantly associated with a decreased risk of MM (odds ratio [OR] = 0.61; 95% confidence interval [CI] = 0.41-0.91; p = 0.014). 30893058

2019
dbSNP: rs1001179
rs1001179
CAT
0.010 GeneticVariation BEFREE Although there was no independent association between either <i>CAT</i> rs1001179 or <i>hOGG1</i> rs1052133 polymorphism and malignant mesothelioma, interaction between both polymorphisms showed a protective effect, OR<sub>int</sub> 0.27 (95% CI 0.10-0.77). 29520212

2018
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
0.010 GeneticVariation BEFREE Although there was no independent association between either <i>CAT</i> rs1001179 or <i>hOGG1</i> rs1052133 polymorphism and malignant mesothelioma, interaction between both polymorphisms showed a protective effect, OR<sub>int</sub> 0.27 (95% CI 0.10-0.77). 29520212

2018
dbSNP: rs1800566
rs1800566
NQO1
0.010 GeneticVariation BEFREE <i>NQO1</i> rs1800566 was significantly associated with increased malignant mesothelioma risk, OR 1.73 (95% CI 1.02-2.96). 29520212

2018
dbSNP: rs243865
rs243865
MMP2
0.010 GeneticVariation BEFREE Carriers of at least one polymorphic <i>MMP2</i> rs243865 allele tended to have a decreased risk for MM (OR = 0.66, 95% CI = 0.44-1.00; P = 0.050). 30018519

2018
dbSNP: rs25487
rs25487
XRCC1
0.010 GeneticVariation BEFREE Our results support the hypothesis that DNA repair gene polymorphisms, particularly XRCC1 Arg399Gln, may modify the response to gemcitabine-platinum combination chemotherapy and, for the first time, show this effect in patients with MM. 22982660

2012
dbSNP: rs746965070
rs746965070
NBN
0.010 GeneticVariation BEFREE Our results support the hypothesis that DNA repair gene polymorphisms, particularly XRCC1 Arg399Gln, may modify the response to gemcitabine-platinum combination chemotherapy and, for the first time, show this effect in patients with MM. 22982660

2012