Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2735839
rs2735839
G 0.800 GeneticVariation GWASDB Multiple newly identified loci associated with prostate cancer susceptibility. 18264097

2008

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE Higher levels of PSA in the presence of KLK3 polymorphism in patients with PC indicated that rs2735839 polymorphism could be a risk factor for increased levels of PSA. 31017705

2019

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE No association was observed between the polymorphism A>G of rs2735839 and risk of PCa. 30413614

2018

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE We did not observe a strong association with the KLK3 variant, reported in previous studies to confer risk for prostate cancer (rs2735839; P = 0.20) but did observe three highly correlated SNPs (rs17632542, rs62113212 and rs62113214) associated with prostate cancer [P = 3.41 × 10(-4), per-allele trend odds ratio (OR) = 0.77, 95% CI = 0.67-0.89]. 21318478

2011

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE When comparing prostate cancer cases with low PSA controls, alleles at genetic markers rs1512268, rs445114, rs10788160, rs11199874, rs17632542, rs266849, and rs2735839 were associated with an increased risk of prostate cancer, but the effect-estimates were attenuated to the null when using high PSA controls (Pheterogeneity in effect-estimates < 0.04). 24753544

2014

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE We confirmed the association of the rs2735839 with high-aggressive prostate cancer (GS ≥8). 25274378

2014

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE Four GWAS replication SNPs (rs2660753, rs13254738, rs10090154, rs2735839) and seven flanking SNPs were associated with CaP aggressiveness (P < 0.05) in three genomic regions: One at 3p12 (EA), seven at 8q24 (5 AA, 2 EA), and three at 19q13 at the kallilkrein-related peptidase 3 (KLK3) locus (two AA, one AA and EA). 22549899

2013

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE The reported risk allele (G) for single nucleotide polymorphism rs2735839 in the KLK3 gene at 19q13 was more frequent in less aggressive prostate cancer patients (0.89) than in more aggressive prostate cancer patients (0.86; nominal P = 0.03) or in controls (0.86; nominal P = 0.04). 18794092

2008

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE The rs61752561 in KLK3 and rs2735839 in the KLK2-KLK3 intergenic region were strongly associated with prostate cancer-specific survival, and rs10486567 in the 7JAZF1 gene were associated with biochemical recurrence. 20460480

2010

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE Two SNPs, rs2735839 at chromosome 19q13 and rs7679673 at 4q24, were associated with prostate cancer-specific survival (P = 7 × 10(-4) and 0.014, respectively). 21367958

2011

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE For the two SNPs that had significant differences between more and less aggressive disease rs2735839 in KLK3 (P = 8.4 x 10(-7)) and rs10993994 in MSMB (P = 0.046), the alleles that are associated with increased risk for PCa were more frequent in patients with less aggressive disease. 19434657

2009

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE In summary, rs752822 and rs2735839 may assist in risk-stratifying GS 7 patients and predict prostate cancer reclassification. 27515962

2016

dbSNP: rs2735839
rs2735839
0.800 GeneticVariation BEFREE Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. 25715684

2015

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation GWASDB Evaluating genetic risk for prostate cancer among Japanese and Latinos. 22923026

2012

dbSNP: rs4242382
rs4242382
A 0.740 GeneticVariation GWASDB Multiple loci identified in a genome-wide association study of prostate cancer. 18264096

2008

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation BEFREE The ORs for a previously identified variant, rs4242382, and prostate cancer increased significantly (P<0.05) with exposure to the organophosphate insecticide fonofos, after correction for multiple testing, with per allele ORnonexposed of 1.17 (95% CI, 0.93-1.48), per allele OR(low) of 1.30 (95% CI, 0.75-2.27), and per allele ORhigh of 4.46 (95% CI, 2.17-9.17; P-interaction=0.002, adjusted P-interaction=0.02). 20978189

2010

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation BEFREE The replicated data suggest that the 8q24 rs4242382-A variation might be associated with increased PCa susceptibility in Asian, Caucasian and African American populations. 25339022

2014

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation GWASDB Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. 23555315

2013

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004

2014

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation BEFREE Blood samples from Finnish men were used to assess the risk of PCa related to three genetic variants (rs4242382, rs138213197, and rs200331695). 25683204

2015

dbSNP: rs4242382
rs4242382
0.740 GeneticVariation GWASDB Multiple newly identified loci associated with prostate cancer susceptibility. 18264097

2008

dbSNP: rs103294
rs103294
0.730 GeneticVariation BEFREE In addition to confirming several associations reported in other ancestry groups, this study identified two new risk-associated loci for prostate cancer on chromosomes 9q31.2 (rs817826, P = 5.45 × 10(-14)) and 19q13.4 (rs103294, P = 5.34 × 10(-16)) in 4,484 prostate cancer cases and 8,934 controls. 23023329

2012

dbSNP: rs103294
rs103294
C 0.730 GeneticVariation GWASDB In addition to confirming several associations reported in other ancestry groups, this study identified two new risk-associated loci for prostate cancer on chromosomes 9q31.2 (rs817826, P = 5.45 × 10(-14)) and 19q13.4 (rs103294, P = 5.34 × 10(-16)) in 4,484 prostate cancer cases and 8,934 controls. 23023329

2012

dbSNP: rs103294
rs103294
0.730 GeneticVariation BEFREE Three SNPs-rs2735839, rs10486567, and rs103294-were associated with biopsy-proven high-aggressive (GS ≥8) prostate cancer (P < 0.05). 25274378

2014

dbSNP: rs103294
rs103294
0.730 GeneticVariation BEFREE A recent prostate cancer (PCa) genome-wide association study (GWAS) identified rs103294, a single nucleotide polymorphism (SNP) located on LILRA3, a key component in the regulation of inflammatory inhibition, to be significantly associated with PCa risk in a Chinese population. 23615473

2013