Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs864622007
rs864622007
AR
0.830 GeneticVariation BEFREE Our results indicate that the specific amino acid residue at position 701, its interaction with the backbone of Ser(778), and the steroidal 17alpha-hydroxyl group of the ligand are all important for the distinct transcriptional responses to progesterone and cortisol of AR mutants, including the prostate cancer mutant L701H. 20007693

2010

dbSNP: rs864622007
rs864622007
AR
0.830 GeneticVariation BEFREE This mutant AR contains two mutations (L701H and T877A) and was previously reported as a high-affinity cortisol/cortisone responsive AR (AR(ccr)) isolated from the androgen-independent human prostate cancer cell lines MDA PCa 2a and 2b (Zhao et al.Nature Med.2000, 6, 703-6). 11906285

2002

dbSNP: rs864622007
rs864622007
AR
0.830 GeneticVariation BEFREE The cortisol/cortisone-responsive AR (AR(ccr)) has two mutations (L701H and T877A) that were found in the MDA PCa human prostate cancer cell lines established from a castrated patient whose metastatic tumor exhibited androgen-independent growth. 11956172

2002

dbSNP: rs864622007
rs864622007
AR
A 0.830 GeneticVariation CLINVAR

dbSNP: rs864622007
rs864622007
AR
0.830 GeneticVariation UNIPROT