| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.030 | GeneticVariation | BEFREE | APC I1307K is unlikely to play a clinically meaningful role in susceptibility to prostate cancer</span>. | 16537703 | 2006 |
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|
0.030 | GeneticVariation | BEFREE | APC I1307K is unlikely to play a clinically meaningful role in susceptibility to prostate cancer</span>. | 16537703 | 2006 |
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|
0.030 | GeneticVariation | BEFREE | Our findings of increased serum t3 level with the APC I1307K allele in prostate cancer patients is not surprising, given the mitogenic potential of t3. | 12856637 | 2003 |
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|
0.030 | GeneticVariation | BEFREE | Our findings of increased serum t3 level with the APC I1307K allele in prostate cancer patients is not surprising, given the mitogenic potential of t3. | 12856637 | 2003 |
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|
0.030 | GeneticVariation | BEFREE | Therefore, our finding, that patients under age 70 carrying the I1307K allele are significantly thinner than those carrying the wild type allele, suggests that the APC I1307K allele is also a prostate cancer risk factor. | 11106824 | 2000 |
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|
0.030 | GeneticVariation | BEFREE | Therefore, our finding, that patients under age 70 carrying the I1307K allele are significantly thinner than those carrying the wild type allele, suggests that the APC I1307K allele is also a prostate cancer risk factor. | 11106824 | 2000 |
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|
0.010 | GeneticVariation | BEFREE | Additional, cDNA array and in silico analyses of prostate cancer tissue suggested that rs2707765 affects <i>APC</i> expression, which in turn is correlated with tumor aggressiveness and patient prognosis. | 27898031 | 2016 |
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|
0.010 | GeneticVariation | BEFREE | Four tSNPs (rs3846716, rs2431238, rs41115, and rs565453) and a specific haplotype (GTAAGA) in the APC tumor suppressor gene were associated with a 0.57- to 0.71-fold lower risk of localized PCa. | 19777185 | 2010 |