|
rs1024611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the gene polymorphisms of MCP-1 (-2518 A/G) (rs1024611), CCR-2 (190 G/A) (rs1799864), ABCA1 (883 G/A) (rs4149313), and IL-17A (-197 G/A) (rs2275913) in obese Turkish children with non-alcoholic fatty liver disease.
|
29733805 |
2019 |
|
rs10272006
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
|
31311600 |
2019 |
|
rs1044498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three of the 14 SNPs were significantly associated with paediatric NAFLD after FDR adjustment, rs738409 (PNPLA3, P = 2.80 × 10<sup>-06</sup> ), rs1044498 (ENPP1, P = 0.0091) and rs780094 (GCKR, P = 0.0281).
|
30444569 |
2019 |
|
rs1057156731
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PPARG H449L mutation was associated with insulin resistance, hypertriglyceridaemia and non-alcoholic fatty liver disease in all affected subjects, but the severity was variable.
|
26756202 |
2016 |
|
rs1057613
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The cumulative effect of the rs1800804 (-164 T/C), rs1057613 and rs3805335 was estimated, and a significant increased trend in the risk of NAF</span>LD with increasing genetic risk score was observed (adjusted P(trend) = 0.014).
|
23738963 |
2014 |
|
rs10750097
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotypes of rs10750097(G/G), rs1263173(A/A), rs17120035(T/T), and rs662799(G/G) performed a significant effect on clinic characteristics in overall series and NAFLD patients, indicating that these polymorphisms may be associated with NAFLD.
|
29735301 |
2018 |
|
rs10865710
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G allele frequency of rs10865710 in NAFLD group (41.1%) was significantly higher than that (34.8%) in controls (p = 0.03).
|
22820754 |
2012 |
|
rs10883437
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we accessed the seven polymorphisms of rs1260326, rs780094 in GCKR, rs2954021 near TRIB1, rs2228603 in NCAN, rs58542926 in TM6SF2, rs12137855 near LYPLAL1, and rs10883437 near CPN1 on NAFLD susceptibility in the Uygur population.
|
30646922 |
2019 |
|
rs11166927
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The nonalcoholic fatty liver disease activity score (scores 1-4 vs 5-8) was associated with SNP rs11166927 on chromosome 8 in the TRAPPC9 region (P = 8.7<sup>-07</sup>).
|
28918882 |
2017 |
|
rs11235972
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A higher prevalence of rs11235972 GG genotype was observed in the NAFLD group compared with the control group.
|
24124336 |
2013 |
|
rs1130864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was conducted to investigate the association of CRP rs1130864 (1444C/T), IL-6 rs1800795 (-174G/C) and LEPR rs1137101 (Q223R) genes with OSA and NAFLD in Asian Indians residing in North India.
|
30001365 |
2018 |
|
rs1131580
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We recently discovered the association of nonalcoholic fatty liver disease, a risk factor for T2DM, with a single nucleotide polymorphism (SNP) in the TRAIL (TNFSF10) gene at site 1595C/T (rs1131580), indicating the possible association of T2DM with this TRAIL polymorphism.
|
24065684 |
2013 |
|
rs1137100
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We report an association between variants of LEPR rs1137100 and rs1137101 with risk of NAFLD.
|
23278404 |
2013 |
|
rs1137100
|
|
|
0.020 |
GeneticVariation |
BEFREE |
LEPR K109R might be a susceptible factor for NAFLD in Southeast Asian population.
|
29974828 |
2018 |
|
rs1137101
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The study was conducted to investigate the association of CRP rs1130864 (1444C/T), IL-6 rs1800795 (-174G/C) and LEPR rs1137101 (Q223R) genes with OSA and NAFLD in Asian Indians residing in North India.
|
30001365 |
2018 |
|
rs1137101
|
|
|
0.030 |
GeneticVariation |
BEFREE |
And LEPR Q223R might be a susceptible factor for NAFLD in Chinese population.
|
29974828 |
2018 |
|
rs1137101
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We report an association between variants of LEPR rs1137100 and rs1137101 with risk of NAFLD.
|
23278404 |
2013 |
|
rs11599176
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SIRT1 gene rs33957861 and rs11599176 polymorphisms significantly reduce the risk of NAFLD and AFLD, while rs35689145 remarkably increases the risk.
|
29189974 |
2018 |
|
rs117542855
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
|
31311600 |
2019 |
|
rs11794552
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
|
31311600 |
2019 |
|
rs11820744
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
|
31311600 |
2019 |
|
rs11868035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We followed up 212 randomly selected, nonobese, nondiabetic, insulin-sensitive participants in a population-based study without NAFLD or metabolic syndrome at baseline who were characterized for the common SREBF-1c gene rs11868035 A/G polymorphism, dietary habits, physical activity, adipokine profile, C-reactive protein (CRP), and circulating markers of endothelial dysfunction.
|
23985808 |
2013 |
|
rs11932595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs11932595 and rs6843722 showed significant associations with NAFLD (empiric P = 0.0449 and 0.023, respectively).
|
17696255 |
2007 |
|
rs11976006
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.
|
31311600 |
2019 |
|
rs12137855
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we accessed the seven polymorphisms of rs1260326, rs780094 in GCKR, rs2954021 near TRIB1, rs2228603 in NCAN, rs58542926 in TM6SF2, rs12137855 near LYPLAL1, and rs10883437 near CPN1 on NAFLD susceptibility in the Uygur population.
|
30646922 |
2019 |