Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE Association of the COMT synonymous polymorphism Leu136Leu and missense variant Val158Met with mood disorders. 25766270

2015

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE COMT Val158Met was not associated with anxiety or mood disorders in either gender. 23928267

2013

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE Results indicate a main as well as a GxE effect of the COMT Val158Met variant and childhood maltreatment on the affect-modulated startle reflex, supporting a complex pathogenetic model of the affect-modulated startle reflex as a basic neurobiological defensive reflex potentially related to anxiety and affective disorders. 22745815

2012

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE The COMT-V158M polymorphism was not associated with suicidal behavior in a Caucasian sample of mood disorder subjects, or with possible clinical or biological endophenotypes. 18828035

2008