|
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
It is evident from our study that Arg72Pro SNP of TP53 gene is connected with higher susceptibility to thyroid cancer especially in young age group, female gender, non-smokers and patients with elevated TSH levels, hence, implicated in thyroid carcinogenesis.
|
25835179 |
2015 |
|
rs1131691014
|
|
|
0.030 |
GeneticVariation |
BEFREE |
It is evident from our study that Arg72Pro SNP of TP53 gene is connected with higher susceptibility to thyroid cancer especially in young age group, female gender, non-smokers and patients with elevated TSH levels, hence, implicated in thyroid carcinogenesis.
|
25835179 |
2015 |
|
rs878854066
|
|
|
0.030 |
GeneticVariation |
BEFREE |
It is evident from our study that Arg72Pro SNP of TP53 gene is connected with higher susceptibility to thyroid cancer especially in young age group, female gender, non-smokers and patients with elevated TSH levels, hence, implicated in thyroid carcinogenesis.
|
25835179 |
2015 |
|
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, there was no significant association between p53 Arg72Pro po</span>lymorphism and thyroid cancer</span> risk under the other three genetic models (Pro vs. Arg: OR = 1.20, 95% CI 0.87-1.67, P = 0.262; ProPro vs. ArgArg: OR = 1.75, 95% CI 0.88-3.50, P = 0.113; ProPro/ArgPro vs. ArgArg: OR = 1.01, 95% CI 0.66-1.55, P = 0.968).
|
24037912 |
2014 |
|
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Subgroup analysis by race showed that TP53 Arg72Pro</span> polym</span>orphism was associated with thyroid carcinoma in Caucasians (ProPro vs. ArgArg/ArgPro, OR = 2.31, 95% CI 1.08 to 4.93, P = 0.03).
|
24375191 |
2014 |
|
rs1131691014
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Subgroup analysis by race showed that TP53 Arg72Pro</span> polym</span>orphism was associated with thyroid carcinoma in Caucasians (ProPro vs. ArgArg/ArgPro, OR = 2.31, 95% CI 1.08 to 4.93, P = 0.03).
|
24375191 |
2014 |
|
rs1131691014
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, there was no significant association between p53 Arg72Pro po</span>lymorphism and thyroid cancer</span> risk under the other three genetic models (Pro vs. Arg: OR = 1.20, 95% CI 0.87-1.67, P = 0.262; ProPro vs. ArgArg: OR = 1.75, 95% CI 0.88-3.50, P = 0.113; ProPro/ArgPro vs. ArgArg: OR = 1.01, 95% CI 0.66-1.55, P = 0.968).
|
24037912 |
2014 |
|
rs878854066
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, there was no significant association between p53 Arg72Pro po</span>lymorphism and thyroid cancer</span> risk under the other three genetic models (Pro vs. Arg: OR = 1.20, 95% CI 0.87-1.67, P = 0.262; ProPro vs. ArgArg: OR = 1.75, 95% CI 0.88-3.50, P = 0.113; ProPro/ArgPro vs. ArgArg: OR = 1.01, 95% CI 0.66-1.55, P = 0.968).
|
24037912 |
2014 |
|
rs878854066
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Subgroup analysis by race showed that TP53 Arg72Pro</span> polym</span>orphism was associated with thyroid carcinoma in Caucasians (ProPro vs. ArgArg/ArgPro, OR = 2.31, 95% CI 1.08 to 4.93, P = 0.03).
|
24375191 |
2014 |
|
rs121912664
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thyroid carcinoma may be associated with the Brazilian founder TP53 p.R337H mutation.
|
28114597 |
2017 |