|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
The A allele of rs965513 polymorphism was shown to be highly associated with risk of thyr</span>oid cancer, with odds ratios of 1.58 (95% CI 1.32-1.90) in all populations, 1.65 (95% CI 1.31-2.07)) in Caucasian populations and 1.49 in Asian populations.
|
27191655 |
2016 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASCAT |
Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.
|
25855579 |
2015 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
These results explain the mechanism by which the risk allele of rs965513 predisposes to thyroid cancer.
|
25918370 |
2015 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
For rs965513, individuals carrying the risk A allele, compared to individuals with the G allele, had 31 % higher risk of thyroid cancer (A vs. G: OR 1.31, 95 % CI 1.17-1.46).
|
26206751 |
2015 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASCAT |
Genome-wide association study on differentiated thyroid cancer.
|
23894154 |
2013 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASDB |
Genome-wide association study on differentiated thyroid cancer.
|
23894154 |
2013 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
The four validated TC SNPs accounted for a relatively large proportion (∼11%) of the sibling relative risk of TC, principally owing to the large effect size of rs965513 (OR 1.74).
|
22282540 |
2012 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
BEFREE |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
GWASDB |
Of those, rs965513 has previously been shown to associate with thyroid cancer.
|
22267200 |
2012 |
|
rs965513
|
|
|
0.860 |
GeneticVariation |
GWASDB |
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
|
20350937 |
2010 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASCAT |
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
|
20350937 |
2010 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASCAT |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
rs965513
|
|
A |
0.860 |
GeneticVariation |
GWASDB |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
rs944289
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
|
25562676 |
2015 |
|
rs944289
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Overall, meta-analysis of rs944289</span> showed 1.11-fold increased risk of thyroid cancer related to the risk T allele (T vs. C: OR 1.11, 95 % CI 1.05-1.17).
|
26206751 |
2015 |
|
rs944289
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Our result demonstrated that rs9442</span>89 polymorphism on 14q13.3 is a low penetrant risk factor for developing TC.
|
25552255 |
2015 |
|
rs944289
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |
|
rs944289
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs) associated with thyroid cancer (TC) risk have been reported: rs2910164 (5q24); rs6983267 (8q24); rs965513 and rs1867277 (9q22); and rs944289 (14q13).
|
22282540 |
2012 |
|
rs944289
|
|
T |
0.850 |
GeneticVariation |
GWASCAT |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
rs944289
|
|
T |
0.850 |
GeneticVariation |
GWASDB |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
|
19198613 |
2009 |
|
rs116909374
|
|
T |
0.840 |
GeneticVariation |
GWASCAT |
A genome-wide association study yields five novel thyroid cancer risk loci.
|
28195142 |
2017 |
|
rs116909374
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Recent genome-wide association (GWA) and candidate studies identified 6 single nucleotide polymorphisms (SNPs; rs966423, rs2439302, rs965513, rs6983267, rs944289, and rs116909374), associated with increased TC risk in Europeans but their effects on disease risk have not been comprehensively tested in Hispanics.
|
27512836 |
2016 |
|
rs116909374
|
|
|
0.840 |
GeneticVariation |
BEFREE |
We found that four SNPs were significantly associated with thyroid cancer in Han Chinese population, while no polymorphism was observed for rs116909374.
|
24591304 |
2014 |
|
rs116909374
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs) were previously reported to be associated with thyroid cancer in European populations in two genome-wide association studies (GWAS): rs965513 (9q22.33), rs944289 (14q13.3), rs116909374 (14q13.3), rs966423 (2q35) and rs2439302 (8p12).
|
23847140 |
2013 |