Gene: EZH2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs267601395
rs267601395
EZH2
0.010 GeneticVariation BEFREE Interestingly, mutation of EZH2 WT alone generated an intermediate resistance phenotype, which is consistent with a previously proposed model of cooperation between EZH2 WT and Y641N mutants to promote tumorigenesis. 25893294

2016
dbSNP: rs267601394
rs267601394
EZH2
0.010 GeneticVariation BEFREE In summary, EZH2(Y641F) can collaborate with Myc to accelerate lymphomagenesis demonstrating a cooperative role of EZH2 mutations in oncogenesis. 24802772

2014