Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.040 | GeneticVariation | BEFREE | We demonstrated that transient transgenic expression of KRAS(G12V) in putative neural stem and/or progenitor cells induced brain tumorigenesis. | 25644510 | 2015 |
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0.040 | GeneticVariation | BEFREE | Administration of a CXCL16-neutralizing antibody to KRAS(G12D) mice reduced activation of PI3K signaling to AKT and NF-κB, blocking carcinogenesis. | 25683115 | 2015 |
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0.040 | GeneticVariation | BEFREE | Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. | 25902334 | 2015 |
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|
0.040 | GeneticVariation | BEFREE | We demonstrated that transient transgenic expression of KRAS(G12V) in putative neural stem and/or progenitor cells induced brain tumorigenesis. | 25644510 | 2015 |
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|
0.040 | GeneticVariation | BEFREE | Administration of a CXCL16-neutralizing antibody to KRAS(G12D) mice reduced activation of PI3K signaling to AKT and NF-κB, blocking carcinogenesis. | 25683115 | 2015 |
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|
0.040 | GeneticVariation | BEFREE | Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. | 25902334 | 2015 |
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|
0.040 | GeneticVariation | BEFREE | We found that TRAIL expression is consistently downregulated in HRAS(G12V)-transformed cells in stepwise tumorigenesis models derived from four different tissues due to DNA hypermethylation of CpG clusters within the TRAIL promoter. | 21697397 | 2011 |
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0.040 | GeneticVariation | BEFREE | We found that TRAIL expression is consistently downregulated in HRAS(G12V)-transformed cells in stepwise tumorigenesis models derived from four different tissues due to DNA hypermethylation of CpG clusters within the TRAIL promoter. | 21697397 | 2011 |