| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
T | 0.740 | GeneticVariation | GWASCAT | 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. | 31562322 | 2019 |
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|
A | 0.740 | GeneticVariation | GWASCAT | Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer. | 26443449 | 2015 |
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0.740 | GeneticVariation | BEFREE | These findings indicate that the PC-susceptibility locus represented by rs12653946 at 5p15 is likely to regulate IRX4 expression in prostate which could suppress PC growth by interacting with the VDR pathway, conferring to PC susceptibility. | 22323358 | 2012 |
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|
0.740 | GeneticVariation | BEFREE | We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer. | 22662242 | 2012 |
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|
0.740 | GeneticVariation | BEFREE | We found that three of the five genetic variants were associated with prostate cancer risk (P = 4.33 × 10(-8) for rs12653946 at 5p15, 4.43 × 10(-5) for rs339331 at 6q22 and 8.42 × 10(-4) for rs9600079 at 13q22, respectively). | 22114074 | 2012 |
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|
T | 0.740 | GeneticVariation | GWASCAT | Evaluating genetic risk for prostate cancer among Japanese and Latinos. | 22923026 | 2012 |
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0.740 | GeneticVariation | BEFREE | The rs12653946 SNP at 5p15 was found to be significantly associated with prostate cancer risk (odds ratio = 1.20, 95% confidence interval: 1.07, 1.34; P = 0.002). | 22085625 | 2011 |
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T | 0.740 | GeneticVariation | GWASCAT | Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. | 20676098 | 2010 |