|
rs339331
|
|
T |
0.760 |
GeneticVariation |
GWASCAT |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population.
|
31562322 |
2019 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
The cumulative effects test of risk alleles (rs rs1983891, rs339331, rs16901966, rs1447295 and rs10090154) showed an increasing risk to PCa in a frequency-dependent manner (ptrend=0.001), and men with more than 3 risk alleles had the most significant susceptibility to PCa (OR=1.99, p=0.001), compared with those who had one risk allele (OR=1.17, p=0.486).
|
26537068 |
2016 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
To validate this approach, we analyzed the 6q22.1 prostate cancer risk locus and identified rs339331 as the top-scoring SNP.
|
26398868 |
2015 |
|
rs339331
|
|
T |
0.760 |
GeneticVariation |
GWASCAT |
Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer.
|
26443449 |
2015 |
|
rs339331
|
|
T |
0.760 |
GeneticVariation |
GWASCAT |
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
|
26034056 |
2015 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Together, our results suggest that rs339331 affects prostate cancer risk by altering RFX6 expression through a functional interaction with the prostate cancer susceptibility gene HOXB13.
|
24390282 |
2014 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Other SNPs were not significantly associated with clinical covariates in prostate cancer (P > 0.05).CONCLUSIONS. rs339331</span> in the RFX6 gene may be associated with prostate cancer as a susceptibility locus in northern Chinese men.
|
23803082 |
2013 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
We successfully replicated the association of rs13385191 (located in the C2orf43 gene, P = 8.60×10(-5)), rs12653946 (P = 1.33×10(-6)), rs1983891 (FOXP4, P = 6.22×10(-5)), and rs339331 (GPRC6A/RFX6, P = 1.42×10(-5)) with prostate cancer.
|
22662242 |
2012 |
|
rs339331
|
|
|
0.760 |
GeneticVariation |
BEFREE |
We found that three of the five genetic variants were associated with prostate cancer risk (P = 4.33 × 10(-8) for rs12653946 at 5p15, 4.43 × 10(-5) for rs339331 at 6q22 and 8.42 × 10(-4) for rs9600079 at 13q22, respectively).
|
22114074 |
2012 |
|
rs339331
|
|
T |
0.760 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
|
20676098 |
2010 |