rs2234693
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Studies on the association between two single nucleotide polymorphisms (SNPs) in estrogen receptor α (ERα), PvuII (rs2234693 T>C) and XbaI (rs9340799 A>G), and the prostate cancer risk are inconsistent.
|
28721070 |
2017 |
rs2234693
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The meta-analysis indicated that ESRα rs9340799 and rs2234693 might contribute to susceptibility and development of PC in European population.
|
29254246 |
2017 |
rs9340799
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Studies on the association between two single nucleotide polymorphisms (SNPs) in estrogen receptor α (ERα), PvuII (rs2234693 T>C) and XbaI (rs9340799 A>G), and the prostate cancer risk are inconsistent.
|
28721070 |
2017 |
rs9340799
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The meta-analysis indicated that ESRα rs9340799 and rs2234693 might contribute to susceptibility and development of PC in European population.
|
29254246 |
2017 |
rs2234693
|
|
|
0.050 |
GeneticVariation |
BEFREE |
However, there was no significant association between ESR1 rs2234693 and PCa risk.
|
26251204 |
2015 |
rs9340799
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicated that ESR1 rs9340799 polymorphism was associated with prosta</span>te cancer risk in overall populations, Caucasians and Africans, while ESR2 rs1256049 polymorphism was associated with prostate cancer risk in Caucasians.
|
24859835 |
2014 |
rs2234693
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: evidence for association with risk and histopathological tumor characteristics in Iranian men.
|
22228197 |
2012 |
rs2234693
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These data suggested that variant rs9340799, but not rs2234693, on ESR1 confers an elevated risk of prostate cancer.
|
23098495 |
2012 |
rs9340799
|
|
|
0.050 |
GeneticVariation |
BEFREE |
For rs9340799, heterozygosity of T/C carriers showed a significant increased prostate cancer risk with a pooled odds ratio (OR) of 1.34 (95% CI = 1.06-1.69) while homozygote C/C carriers showed an increased but not statistically significant association with prostate cancer risk (pooled OR = 1.29, 95% CI = 0.94-1.79).
|
23098495 |
2012 |
rs9340799
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: evidence for association with risk and histopathological tumor characteristics in Iranian men.
|
22228197 |
2012 |
rs2077647
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study suggests that rs2077647 polymorphism may be a risk factor for prostate cancer especially in patients diagnosed before the age of 60, while rs3798577 polymorphism could probably serve rather as promoting factor in combination with other polymorphisms in estrogen receptor alpha contributing preferably to development of high-grade carcinomas.
|
25828708 |
2015 |
rs2077647
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The combination of the TTTA long repeats and the minor alleles of rs10046 in CYP19A1 and rs2077647 in ESR-alpha was a high risk for prostate cancer despite greater than or equal to 60 mg isoflavones/day.
|
19952760 |
2010 |
rs3798577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study suggests that rs2077647 polymorphism may be a risk factor for prostate cancer especially in patients diagnosed before the age of 60, while rs3798577 polymorphism could probably serve rather as promoting factor in combination with other polymorphisms in estrogen receptor alpha contributing preferably to development of high-grade carcinomas.
|
25828708 |
2015 |
rs2228480
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An interaction between intake level of phytoestrogen and genotypes of ESR1 Ex1-192G>C (rs746432) and between intake level of phytoestrogen and genotypes of ESR1 Ex8+229G>A (rs2228480) and risk of prostate cancer was observed (p = 0.0009 and p = 0.044, respectively).
|
19654868 |
2009 |
rs746432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An interaction between intake level of phytoestrogen and genotypes of ESR1 Ex1-192G>C (rs746432) and between intake level of phytoestrogen and genotypes of ESR1 Ex8+229G>A (rs2228480) and risk of prostate cancer was observed (p = 0.0009 and p = 0.044, respectively).
|
19654868 |
2009 |