Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Significant associations with BC were observed for rs3803662 (dominant comparison: OR, 0.89; 95% CI, 0.84-0.95; P = .0008; recessive comparison: OR, 1.17; 95% CI, 1.07-1.28; P = .0004; over-dominant comparison: OR, 1.07; 95% CI, 1.02-1.11; P = .002; allele comparison: OR, 0.90; 95% CI, 0.86-0.95; P = .0002), rs8051542 (dominant comparison: OR, 0.87; 95% CI, 0.83-0.91; P < .0001; recessive comparison: OR, 1.19; 95% CI, 1.11-1.28; P < .0001; over-dominant comparison: OR, 1.07; 95% CI, 1.02-1.11; P = .004; allele comparison: OR, 0.89; 95% CI, 0.86-0.91; P < .0001), and rs12922061 (dominant comparison: OR, 0.83; 95% CI, 0.73-0.93; P = .002; over-dominant comparison: OR, 1.43; 95% CI, 1.27-1.61; P < .0001) polymorphisms in the overall population. 31324582

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE TOX3-rs3803662, may confer some degrees of risk of breast cancer in Iranian population. 30515698

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE SNP rs3803662 (TOX3/TNRC9) is an independent prognostic factor for breast cancer in Henan Han Population. 31317673

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Given that <i>TOX3</i> mRNA is a target of miR-182, and that both the <i>TOX3</i> rs3803662-T and pri-miR-182 rs4541843-T alleles are associated with increased BC risk, we evaluated their combined effect. 30135399

2018

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE No statistically significant association was found between the rs3803662 polymorphism and breast cancer in patients or healthy controls. 29683073

2018

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE This meta-analysis suggested that TOX3 rs3803662 polymorphism was associated with increased breast cancer risk. 29578175

2018

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE BC patients (n = 1687) randomly sampled in an adjuvant, randomized phase III trial (SUCCESS A study) were genotyped for nine BC risk SNPs: rs17468277 <i>(CASP8)</i> , rs2981582 <i>(FGFR2)</i> , rs13281615(8q24), rs3817198 <i>(LSP1)</i> , rs889312 <i>(MAP3K1)</i> , rs3803662 <i>(TOX3)</i> , rs13387042(2q35), rs4973768 <i>(SLC4A7)</i> , rs6504950 <i>(COX11)</i> . 28757652

2017

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE The present meta-analysis suggests that rs3803662 polymorphism is significantly associated with breast cancer risk in Caucasian women, and we did not find the association in Asian women. 27350156

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE A case‑control study (90‑100 cases; 90‑100 controls) was performed to evaluate five genetic variants of three genes, including FGFR2 (SNPs: rs1219648, rs2981582), TNRC9 (SNPs: rs8051542, rs3803662) and MAP3K1 (SNP: rs889312) as BC risk factors in Pakistani women. 27572905

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Five common breast cancer susceptibility loci from GWAS are not strongly associated with breast cancer risk among the Han Chinese of the Henan province; only rs3803662 (T</span>OX3/TNRC9) is confirmed to increase the risk of breast cancer. 26803517

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE The TNRC9 rs3803662 C>T polymorphism is greatly related to increased risk of BC, in both Asian and Caucasian populations. 27525937

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Subjects carrying an allele of rs2981582 had reduced breast cancer risk (GA vs GG: OR=0.444, 95% CI=0.262-0.752; AA vs GG: OR=0.579, 95% CI=0.342-0.983). rs3803662 and rs3817198 SNPs did not significantly differ between cases and controls (P=0.408 and 0.116, respectively). 26911390

2016

dbSNP: rs3803662
rs3803662
A 0.900 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625

2015

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE In Asian populations, there were significant associations of rs3803662</span> and rs8051542 with breast cancer risk. 26239137

2015

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE In conclusion, we show that there is little overlap between the breast cancer risk single nucleotide polymorphisms (SNPs) identified so far and the SNPs associated with breast cancer prognosis, with the possible exceptions of LSP1-rs3817198 and TNRC9-rs3803662. 25611573

2015

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE These results indicate an additive effect of the TOX3 rs3803662 and 2q35 rs13387042 alleles for BC risk. 24532140

2014

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE We conclude that SNP rs3803662 is a putative risk factor for breast cancer in Chinese Han women. 24446301

2014

dbSNP: rs3803662
rs3803662
A 0.900 GeneticVariation GWASCAT Large-scale genotyping identifies 41 new loci associated with breast cancer risk. 23535729

2013

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Recently, genetic polymorphism (rs3803662C>T) in TOX3 was reported to induce the risk of breast cancer. 24069142

2013

dbSNP: rs3803662
rs3803662
T 0.900 GeneticVariation GWASCAT Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733

2013

dbSNP: rs3803662
rs3803662
A 0.900 GeneticVariation GWASCAT Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. 23544012

2013

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE We confirmed associations between rs13387042 (2q35), rs4973768 (SLC4A7), rs10941679 (5p12), rs2981582 (FGFR2), rs3817198 (LSP1), rs3803662 (TOX3), and rs6504950 (STXBP4) with breast cancer. 23893088

2013

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Ten of the 11 breast cancer susceptibility loci reported by consortia also showed associations in our predominantly Caucasian study population, and the associations were independent of BMI; four FGFR2 SNPs and TNRC9-rs3803662 were among the most notable associations. 23717390

2013

dbSNP: rs3803662
rs3803662
T 0.900 GeneticVariation GWASCAT Genome-wide association study of breast cancer in the Japanese population. 24143190

2013

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Three SNPs were significantly associated with a breast cancer risk in multivariate analysis: rs2046210 (per allele OR=1.37 [95% CI: 1.11-1.70]), rs3757318 (OR=1.33[1.05-1.69]), and rs3803662 (OR=1.28 [1.07-1.55]). 24289300

2013