|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
BARD1 Cys557Ser was associated with an increased BC risk (P = 0.04, OR = 3.4 [95 % CI 1.2-10.2]) among cases belonging to families with a strong family history of BC.
|
22544576 |
2012 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The BARD1 Cys557Ser variant was not significantly associated with risk of breast cancer from single SNP analysis, with a pooled effect estimate of 0.90 (95% CI: 0.71-1.15) in BRCA1 carriers and 0.87 (95% CI: 0.59-1.29) in BRCA2 carriers.
|
21393566 |
2011 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis strongly suggests that BARD1 Cys557Ser mutation is not associated with increased breast cancer risk.
|
21809034 |
2011 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We conclude that the BARD1 Cys557Ser variant is not associated with breast cancer risk.
|
18481171 |
2009 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
There was no clear association between the presence of the BARD1 Cys557Ser allele and breast cancer in Poland.
|
17333333 |
2008 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These results provide further evidence that BARD1 Cys557Ser confers a slightly increased risk of breast cancer in women.
|
16825437 |
2006 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These results suggest that the contribution of the BARD1 germline variants to breast cancer predisposition is very limited, and that neither Cys557Ser nor Val507Met have an effect on familial breast cancer susceptibility.
|
16333312 |
2006 |
|
rs28997576
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Lobular and medullary breast carcinomas were overrepresented amongst Cys557Ser carriers.
|
16768547 |
2006 |
|
rs1048108
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SNP sites rs2229571 and rs1048108 of BARD1 are associated with a lower risk of breast cancer but not rs2070094.
|
23966609 |
2013 |
|
rs2229571
|
|
|
0.020 |
GeneticVariation |
BEFREE |
SNP sites rs2229571 and rs1048108 of BARD1 are associated with a lower risk of breast cancer but not rs2070094.
|
23966609 |
2013 |
|
rs1048108
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR=1.81, 95% CI=1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk (adjusted OR=0.74, 95% CI=0.56-0.99).
|
17028982 |
2007 |
|
rs2229571
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer.
|
17028982 |
2007 |
|
rs113211432
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the contribution of the BARD1 germline variants to breast cancer predisposition is very limited, and that neither Cys557Ser nor Val507Met have an effect on familial breast cancer susceptibility.
|
16333312 |
2006 |
|
rs2070094
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the contribution of the BARD1 germline variants to breast cancer predisposition is very limited, and that neither Cys557Ser nor Val507Met have an effect on familial breast cancer susceptibility.
|
16333312 |
2006 |
|
rs386654966
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the contribution of the BARD1 germline variants to breast cancer predisposition is very limited, and that neither Cys557Ser nor Val507Met have an effect on familial breast cancer susceptibility.
|
16333312 |
2006 |
|
rs113211432
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genetic polymorphism of BARD1 (Val/Met 507) could be useful in the selection of postmenopausal women at a high risk for developing breast cancer.
|
14550946 |
2003 |
|
rs2070094
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genetic polymorphism of BARD1 (Val/Met 507) could be useful in the selection of postmenopausal women at a high risk for developing breast cancer.
|
14550946 |
2003 |
|
rs386654966
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genetic polymorphism of BARD1 (Val/Met 507) could be useful in the selection of postmenopausal women at a high risk for developing breast cancer.
|
14550946 |
2003 |
|
rs376256852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants (Thr598Ile and Ile692Thr) were not detected in any of the 659 sporadic breast cancer cases and controls and were assessed for segregation with breast cancer in the families of the probands.
|
17972171 |
2008 |
|
rs587782555
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants (Thr598Ile and Ile692Thr) were not detected in any of the 659 sporadic breast cancer cases and controls and were assessed for segregation with breast cancer in the families of the probands.
|
17972171 |
2008 |