rs1044396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gene polymorphisms of CHRNA3 (rs578776) and CHRNA4 (rs1044396 and rs2229959) were associated with the success of smoking cessation after the diagnosis of lung cancer, which should be considered in the management of smoking cessation after patients are diagnosed with lung cancer.
|
31402126 |
2020 |
rs121912654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.
|
31067569 |
2020 |
rs139600787
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among all lung cancer-linked mutants that we tested, A46T Parkin failed to translocate onto mitochondria and could not recruit downstream mitophagic regulators, including optineurin (OPTN) and TFEB, whereas N254S and R275W Parkin displayed slower mitochondrial translocation than WT Parkin.
|
31285534 |
2020 |
rs2229959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gene polymorphisms of CHRNA3 (rs578776) and CHRNA4 (rs1044396 and rs2229959) were associated with the success of smoking cessation after the diagnosis of lung cancer, which should be considered in the management of smoking cessation after patients are diagnosed with lung cancer.
|
31402126 |
2020 |
rs2239611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggested that rs2284749 and rs2239611 in the ST6GAL1 gene are associated with lung carcinoma risk in the Chinese Han population.
|
31794515 |
2020 |
rs2284749
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggested that rs2284749 and rs2239611 in the ST6GAL1 gene are associated with lung carcinoma risk in the Chinese Han population.
|
31794515 |
2020 |
rs483352697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.
|
31067569 |
2020 |
rs756402191
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.
|
31067569 |
2020 |
rs776983107
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among all lung cancer-linked mutants that we tested, A46T Parkin failed to translocate onto mitochondria and could not recruit downstream mitophagic regulators, including optineurin (OPTN) and TFEB, whereas N254S and R275W Parkin displayed slower mitochondrial translocation than WT Parkin.
|
31285534 |
2020 |
rs778009684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among all lung cancer-linked mutants that we tested, A46T Parkin failed to translocate onto mitochondria and could not recruit downstream mitophagic regulators, including optineurin (OPTN) and TFEB, whereas N254S and R275W Parkin displayed slower mitochondrial translocation than WT Parkin.
|
31285534 |
2020 |
rs10053847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>IL-7R</i> rs10053847 was correlated with a decreased LC risk, while <i>IL-7R</i> rs10213865 was correlated with an elevated lung adenocarcinoma risk, implying these two SNPs might play essential roles in LC risk evaluation.
|
31354347 |
2019 |
rs10054203
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four polymorphisms exhibited prominent associations with lung cancer risk, including rs7726159 (OR = 1.34, 95%CI: 1.18-1.52, P = 7.78 × 10<sup>-6</sup> ), rs10054203 (OR = 1.29, 95%CI: 1.13-1.46, P = 1.37 × 10<sup>-4</sup> ), rs2736107 (OR = 1.28, 95%CI: 1.11-1.47, P = 5.14 × 10<sup>-4</sup> ), and rs2853677 (OR = 1.23, 95%CI: 1.08-1.39, P = 0.002).
|
30680798 |
2019 |
rs10213865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>IL-7R</i> rs10053847 was correlated with a decreased LC risk, while <i>IL-7R</i> rs10213865 was correlated with an elevated lung adenocarcinoma risk, implying these two SNPs might play essential roles in LC risk evaluation.
|
31354347 |
2019 |
rs1026411
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we chose four single nucleotide polymorphisms (SNPs) in lncRNA-<i>PCAT1</i> (rs1026411 G>A, rs12543663 A>C, rs710886 T>C, and rs16901904 T>C) to investigate the association between genetic variant in lncRNA-<i>PCAT1</i> and susceptibility to lung cancer.
|
31464517 |
2019 |
rs10421768
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs10421768 in HAMP showed a borderline statistically significant correlation with lung cancer risk (OR = 2.83, p = 0.05).
|
30640897 |
2019 |
rs1042711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic model analysis shows that rs1042711 and rs1560642 were associated with increased risk of lung cancer; whereas rs7025417, rs5756523, and rs2284033 were associated with decreased disease risk (p < 0.05).
|
31685439 |
2019 |
rs1043994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the rs3815188 variant and rs1043994 variant of the Notch3 gene is associated with lung cancer risk in patients of Turkish origin.
|
30806291 |
2019 |
rs1046175
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aims to explore the relationship between SFTPB rs7316, rs9752 and PAOX rs1046175 gene polymorphisms and the diagnostic value of plasma Pro-SFTPB and DAS in patients with Chinese Han lung cancer.
|
31016788 |
2019 |
rs10519717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, rs1489759 and rs3131837 were associated with lung cancer in various genetic models. rs1489758, rs1489759, and rs10519717 were also associated with lung cancer in serious COPD patients.
|
29915314 |
2019 |
rs1057519784
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we report that both <i>ALK</i>-mutant L1196M and EMT were concomitantly detected in a single crizotinib-resistant lesion in a patient with <i>ALK</i>-rearranged lung cancer.
|
30737231 |
2019 |
rs1064607
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In stratified analyses by gender, three (rs1064607, rs3796283 and rs2378456) of LPP gene were associated with a significantly increased susceptibility for lung cancer among male population.
|
30621612 |
2019 |
rs1065852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study revealed that rs1065852, rs2043449, rs2762s934, and rs6068816 of CYPs were associated with LC susceptibility in the Northwestern Chinese Han population; CYP2D6 and CYP20A1 were overexpressed and correlated with prognosis of LC.
|
31264381 |
2019 |
rs10680577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Ins/Del polymorphism (rs10680577) in RERT-lncRNA was correlated with the risk, major clinicopathological features, and prognosis of lung cancer patients, and the patients with Ins/Del + Del/Del genotype carriers had higher expressions of RERT-lncRNA and EGLN2 than those with Ins/Ins carriers.
|
30073577 |
2019 |
rs11137037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the variant GT allele of rs12674822 had a higher risk of lung cancer than wild-type (GG) carriers, while the presence of the CC genotype at rs11137037 was associated with higher clinical stage disease compared with having the AA genotype.
|
31281470 |
2019 |
rs1128503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1799971 and rs1323040 polymorphisms of the <i>OPRM1</i> gene and rs2032582 and rs1128503 polymorphisms of the <i>ABCB1</i> gene are related to the analgesic effect and consumed dose of sufentanil in Chinese Han patients undergoing radical operation of lung cancer.
|
30455395 |
2019 |