|
rs6265
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The common 196G > A single-nucleotide polymorphism of BDNF gene, resulting in a valine 66 to methionine (Val66Met), is related with behaviour disorders and substance abuse.
|
19517061 |
2009 |
|
rs759834365
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The common 196G > A single-nucleotide polymorphism of BDNF gene, resulting in a valine 66 to methionine (Val66Met), is related with behaviour disorders and substance abuse.
|
19517061 |
2009 |
|
rs324420
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms (SNPs) in the CNR1 (rs2023239) and FAAH (rs324420) genes, associated previously with substance abuse and functional changes in cannabinoid regulation, were examined in a sample of daily marijuana smokers.
|
18705688 |
2008 |
|
rs324420
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Owing to the importance of endocannabinoid system in addiction, the Pro129Thr polymorphism in the FAAH gene has reportedly been associated with substance abuse and dependence in a Caucasian population.
|
17621164 |
2007 |
|
rs6265
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The results suggest that the BDNF Val66M</span>et polymorphism or a nearby locus may be involved in the pathogenesis of substance abuse.
|
16109452 |
2005 |
|
rs759834365
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The results suggest that the BDNF Val66M</span>et polymorphism or a nearby locus may be involved in the pathogenesis of substance abuse.
|
16109452 |
2005 |
|
rs25531
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The main aim of this study is to evaluate the genetic association of DRD4 (48 bp-VNTR) and SLC6A4 (rs25531 and 5-HTTLPR VNTR) gene polymorphisms with SUD susceptibility among the Jordanian Arab population.
|
31809838 |
2020 |
|
rs17228616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, no statistically significant association of rs17228616 SNP with substance abuse disorder was found.
|
31129131 |
2019 |
|
rs1803274
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biochemical Analysis and Association of Butyrylcholinesterase SNPs rs3495 and rs1803274 with Substance Abuse Disorder.
|
30707402 |
2019 |
|
rs3495
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biochemical Analysis and Association of Butyrylcholinesterase SNPs rs3495 and rs1803274 with Substance Abuse Disorder.
|
30707402 |
2019 |
|
rs2044081
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Exploiting the IMAGEN database (Schumann et al., 2010), we explored in a human adolescent population whether possession of the minor (T) variant of the single nucleotide polymorphism (SNP) rs2044081 is associated with performance of tasks measuring aspects of impulsivity, and reward sensitivity that are implicated in drug and alcohol abuse.
|
28261068 |
2017 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Studies have associated the rs4680 genotype with impulsivity as a symptom in attention deficit hyperactivity disorder and substance abuse.
|
23440431 |
2013 |
|
rs1039002
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Bipolar disorder with psychosis and/or substance abuse in the absence of alcohol dependence was associated with the rare variant rs1039002 in the vicinity of the gene phosphodiesterase 10A (PDE10A) on chromosome 6q27 (p = 1.7×10⁻⁸).
|
22205951 |
2011 |
|
rs746682028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The common 196G > A single-nucleotide polymorphism of BDNF gene, resulting in a valine 66 to methionine (Val66Met), is related with behaviour disorders and substance abuse.
|
19517061 |
2009 |
|
rs1189608960
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study of human chromosome 12 loci revealed that the Ser127Gly polymorphism in PTPRB is associated with substance abuse vulnerability in three independent case-control samples (European-American from COGA families, USA, n = 177, P = 0.047; European-American from Maryland, USA, n = 650, P = 0.018; and African-American from Maryland, USA, n = 331, P = 0.009).
|
18361428 |
2008 |
|
rs135745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was also no significant association between rs135745 and the clinical characteristics of methamphetamine dependence and co-morbid methamphetamine psychosis (e.g., age of first consumption, latency of psychosis, prognosis of psychosis after therapy, spontaneous relapse of psychotic symptoms, and poly-substance abuse status).
|
18991847 |
2008 |
|
rs2023239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two single nucleotide polymorphisms (SNPs) in the CNR1 (rs2023239) and FAAH (rs324420) genes, associated previously with substance abuse and functional changes in cannabinoid regulation, were examined in a sample of daily marijuana smokers.
|
18705688 |
2008 |
|
rs2465811
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study of human chromosome 12 loci revealed that the Ser127Gly polymorphism in PTPRB is associated with substance abuse vulnerability in three independent case-control samples (European-American from COGA families, USA, n = 177, P = 0.047; European-American from Maryland, USA, n = 650, P = 0.018; and African-American from Maryland, USA, n = 331, P = 0.009).
|
18361428 |
2008 |
|
rs1799971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these, C17T and A118G, have been reported to be associated with substance abuse.
|
18181266 |
2007 |
|
rs1799972
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these, C17T and A118G, have been reported to be associated with substance abuse.
|
18181266 |
2007 |
|
rs3278
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3278 is associated reliably with substance abuse vulnerability in (1) a European American sample selected from pedigrees within the Collaborative Study on the Genetics of Alcoholism (COGA; nominal P = 0.03); (2) an African American sample recruited by the National Institute on Drug Abuse (NIDA; nominal P = 0.008); and (3) a NIDA European American sample (P = 0.001).
|
17624982 |
2007 |
|
rs6296
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Substance abuse disorder and major depression appear to be associated with the h5-HTR(1B) G861C locus in the patient population, but other psychopathologies such as bipolar disorder, schizophrenia, alcoholism, and suicide attempts were not found to be associated with this polymorphism.
|
12496953 |
2003 |
|
rs1801028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse.
|
9650635 |
1998 |