Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs199473282
rs199473282
0.840 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473282
rs199473282
0.840 GeneticVariation UNIPROT Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)-subunit. 10618304

2000

dbSNP: rs199473282
rs199473282
0.840 GeneticVariation UNIPROT Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent. 10532948

1999

dbSNP: rs199473282
rs199473282
0.840 GeneticVariation UNIPROT Genetic basis and molecular mechanism for idiopathic ventricular fibrillation. 9521325

1998

dbSNP: rs137854615
rs137854615
0.830 GeneticVariation UNIPROT Natural history of Brugada syndrome: insights for risk stratification and management. 11901046

2002

dbSNP: rs137854615
rs137854615
0.830 GeneticVariation UNIPROT Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. 11410597

2001

dbSNP: rs199473083
rs199473083
0.820 GeneticVariation UNIPROT Natural history of Brugada syndrome: insights for risk stratification and management. 11901046

2002

dbSNP: rs199473623
rs199473623
0.810 GeneticVariation UNIPROT Electrophysiological characteristics of a SCN5A voltage sensors mutation R1629Q associated with Brugada syndrome. 24167619

2014

dbSNP: rs199473062
rs199473062
0.810 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473101
rs199473101
0.810 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473220
rs199473220
0.810 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473623
rs199473623
0.810 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs28937318
rs28937318
0.810 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473220
rs199473220
0.810 GeneticVariation UNIPROT Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies. 19251209

2009

dbSNP: rs28937318
rs28937318
0.810 GeneticVariation UNIPROT Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies. 19251209

2009

dbSNP: rs199473101
rs199473101
0.810 GeneticVariation UNIPROT Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation. 18378609

2008

dbSNP: rs199473220
rs199473220
0.810 GeneticVariation UNIPROT Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients. 12106943

2002

dbSNP: rs28937318
rs28937318
0.810 GeneticVariation UNIPROT Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome. 11823453

2002

dbSNP: rs199473305
rs199473305
0.800 GeneticVariation UNIPROT MOG1 rescues defective trafficking of Na(v)1.5 mutations in Brugada syndrome and sick sinus syndrome. 23420830

2013

dbSNP: rs137854616
rs137854616
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473055
rs199473055
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473058
rs199473058
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473082
rs199473082
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473168
rs199473168
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011

dbSNP: rs199473169
rs199473169
0.800 GeneticVariation UNIPROT An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. 20129283

2011