Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE We investigated the effects of the rs1360780 polymorphism of the hypothalamic-pituitary-axis related gene FKBP5 in combination with early life stress (ELA) on the structure of hippocampal subfields in MDD. 30986730

2019

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE We investigated the interactive effects of FKBP5 rs1360780 allelic variants, DNA methylation, and the diagnosis of MDD on structural changes of the entire brain. 28198448

2017

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE The rs1360780 SNP in this gene (T allele vs C homozygous) has been found to be associated with major depressive disorder (MDD). 26076833

2016

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE However, after removing one heterogeneous German study, as indicated by sensitivity analysis, both the rs1360780 T-allele (Z = 2.95, P = 0.003, OR = 1.06, 95% CI = 1.02-1.11) and the rs3800373 C-allele (Z = 3.05, P = 0.002, OR = 1.07, 95% CI 1.02-1.12) were significantly associated with MDD in a fixed-effect model. 27601205

2016

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE The FKBP5 polymorphism rs1360780 influences the effect of an algorithm-based antidepressant treatment and is associated with remission in patients with major depression. 26645208

2016

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE In the present study, we investigated whether the FKBP5 polymorphism rs1360780 and lifetime history of major depression are associated with DNA methylation and FKBP5 gene expression after psychosocial stress. 25522420

2014

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE Significant associations between AD and MDD have been found for three polymorphisms mainly in females (TPH1 A218C, MAOA VNTR and BDNF Val66Met) and one polymorphism in the total population only (FKBP5 rs1360780). 23157339

2013

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE The results showed that the T allele of rs1360780 was more frequent among the patients affected by MDD with a comorbidity of anxiety disorders, compared to those without (P < .001). 23861224

2013

dbSNP: rs1360780
rs1360780
0.090 GeneticVariation BEFREE Change in FKBP5 expression correlated with change in Beck Depression Inventory (BDI) for MDD → euthymic comparison in GG genotype of rs3800373 (P = .013) and TT carriers of rs1360780 (P = .02). 20726698

2010