In this study, we first aimed to examine whether this polymorphism is associated with cancer risk based on the latest published data, and consistent with previous meta-analyses, a significant association between the rs2070600 polymorphism and cancer risk was observed (A versus G: OR = 1.25; 95% CI = 1.12-1.40).
Thus, this meta-analysis revealed that 82G/S polymorphism i</span>s associated with a significantly increased risk of cancer, while -374T/A polymorphism is associated with a reduced risk of cancers.