rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs351855 G>A polymorphism was associated with an increased cancer risk under the recessive model (OR=1.19, 95% CI=1.01-1.41).
|
28445975 |
2017 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The FGFR4 Gly388Arg polymorphism is associated with cancer and cardiovascular diseases, but its association with hypertension is unclear.
|
28650667 |
2017 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Thus, our findings elucidate the molecular mechanism behind the genetic association of rs351855 with accelerated cancer progression and suggest that germline variants of cell-surface molecules that recruit STAT3 to the inner cell membrane are a significant risk for cancer prognosis and disease progression.
|
26675719 |
2015 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that FGFR4 rs351855G/A polymorphism is associated with increased susceptibility to NHL and could be used as a marker for predicting the prognosis of the malignancy.
|
24248544 |
2014 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results suggest that the FGFR4 Gly388Arg polymorphism is not a risk factor for GC cancer initiation but that it is a useful prognostic marker for GC patients when the tumor is relatively small, well differentiated, or at an early clinical stage.
|
23901234 |
2013 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer.
|
22971346 |
2012 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results provide evidence of a role for the FGFR4 Gly388Arg polymorphism in modulating patients' outcome in different types of cancer, thus offering to clinicians a new marker to predict predisposition to poor survival in cancer patients.
|
21412156 |
2011 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis suggests that the FGFR4 Gly388Arg polymorphism most likely contributes to susceptibility to cancer, especially in Asians.
|
20638838 |
2010 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Gly388Arg polymorphism in the fibroblast growth factor receptor 4 (FGFR4) gene has been reported to influence prognosis in a wide variety of cancer types.
|
17519899 |
2007 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Clinical investigations of an FGFR4 germline polymorphism, resulting in substitution of glycine by arginine at codon 388 (G388 to R388), have shown a correlation between FGFR4 R388 and aggressive disease progression in cancer patients.
|
16109476 |
2006 |
rs351855
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Gly388Arg polymorphism in the FGFR4 gene was reported to modulate cancer cell migration in vitro and to be associated with breast, colon, and prostate cancer prognostic parameters.
|
16061909 |
2005 |