Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE The rs351855 G>A polymorphism was associated with an increased cancer risk under the recessive model (OR=1.19, 95% CI=1.01-1.41). 28445975

2017

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE The FGFR4 Gly388Arg polymorphism is associated with cancer and cardiovascular diseases, but its association with hypertension is unclear. 28650667

2017

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE Thus, our findings elucidate the molecular mechanism behind the genetic association of rs351855 with accelerated cancer progression and suggest that germline variants of cell-surface molecules that recruit STAT3 to the inner cell membrane are a significant risk for cancer prognosis and disease progression. 26675719

2015

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE These results suggest that FGFR4 rs351855G/A polymorphism is associated with increased susceptibility to NHL and could be used as a marker for predicting the prognosis of the malignancy. 24248544

2014

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE Our results suggest that the FGFR4 Gly388Arg polymorphism is not a risk factor for GC cancer initiation but that it is a useful prognostic marker for GC patients when the tumor is relatively small, well differentiated, or at an early clinical stage. 23901234

2013

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. 22971346

2012

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE These results provide evidence of a role for the FGFR4 Gly388Arg polymorphism in modulating patients' outcome in different types of cancer, thus offering to clinicians a new marker to predict predisposition to poor survival in cancer patients. 21412156

2011

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE Our meta-analysis suggests that the FGFR4 Gly388Arg polymorphism most likely contributes to susceptibility to cancer, especially in Asians. 20638838

2010

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE The Gly388Arg polymorphism in the fibroblast growth factor receptor 4 (FGFR4) gene has been reported to influence prognosis in a wide variety of cancer types. 17519899

2007

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE Clinical investigations of an FGFR4 germline polymorphism, resulting in substitution of glycine by arginine at codon 388 (G388 to R388), have shown a correlation between FGFR4 R388 and aggressive disease progression in cancer patients. 16109476

2006

dbSNP: rs351855
rs351855
0.100 GeneticVariation BEFREE The Gly388Arg polymorphism in the FGFR4 gene was reported to modulate cancer cell migration in vitro and to be associated with breast, colon, and prostate cancer prognostic parameters. 16061909

2005