Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743890
rs5743890
0.830 GeneticVariation BEFREE Leukocyte telomere length (LTL), <i>MUC5B</i> rs35705950 and <i>TOLLIP</i> rs5743890 have been associated with idiopathic pulmonary fibrosis (IPF).In this observational cohort study, we assessed the associations between these genomic markers and outcomes of survival and rate of disease progression in patients with interstitial pneumonia with autoimmune features (IPAF, n=250) and connective tissue disease-associated interstitial lung disease (CTD-ILD, n=248). 30635297

2019

dbSNP: rs5743890
rs5743890
0.830 GeneticVariation BEFREE We measured two common single-nucleotide polymorphisms associated with IPF (MUC5B rs35705950 and TOLLIP rs5743890) and telomere length in peripheral blood leucocytes, and assessed their associations with chronic hypersensitivity pneumonitis risk, survival, and clinical, radiographic, and pathological features. 28648751

2017

dbSNP: rs5743890
rs5743890
A 0.830 GeneticVariation GWASCAT Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. 24429156

2013

dbSNP: rs5743890
rs5743890
0.830 GeneticVariation BEFREE Individuals who developed IPF despite having the protective TOLLIP minor allele of rs5743890 carried an increased mortality risk (meta-analysis with fixed-effect model: hazard ratio 1·72 [95% CI 1·24-2·38]; p=0·0012). 24429156

2013

dbSNP: rs5743890
rs5743890
A 0.830 GeneticVariation GWASDB Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. 24429156

2013