|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Although longer hospitalization stay was observed in patients with the rs1333049-C allele, this polymorphism was not related to angiographic severity of CAD, LVEF, and occurrence of MACE after MI.
|
19548844 |
2009 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We genotyped the rs1333049 single-nucleotide polymorphism in 593 Caucasian individuals with stable coronary artery disease recruited in the Heart and Soul Study.
|
19171343 |
2009 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Higher FRS and PWV and the presence of rs2943634 risk allele were independent predictors of CAD (Nagelkerke R(2) 0·252, P < 0·001), while higher FRS and the presence of rs1333049 risk allele were independent predictors of multivessel CAD (Nagelkerke R(2) 0·190, P < 0·001).
|
24942486 |
2014 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP), rs1333049 on chromosome 9p21.3 has been strongly associated with CAD and myocardial infarction.
|
23787071 |
2013 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Of 1095 CAD diagnosis-free participants, 52% were heterozygous (CG) and 22% were homozygous (CC) for the risk C allele rs1333049.
|
21852414 |
2011 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
GWASDB |
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
23202125 |
2013 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The polymorphic variants of Apo-A5; rs2266788 (C), 9p21.3; rs1333049 (C) rs2383207 (A) are associated with CAD, its severity and exerts the risk of MI in North Indian population.
|
29309886 |
2018 |
|
rs1333049
|
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
To investigate whether the SNP rs1333049 located on the 9p21 chromosome is an independent risk factor for CAD in a Portuguese population.
|
21874923 |
2011 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In the case-control study, only haplotypes at 1 block tagged by rs1333049 associated with CAD more so than MI.
|
23729007 |
2013 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI).
|
20231156 |
2010 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Further subgroup analyses showed that rs1333040, rs1333049 and rs2383207 polymorphisms were significantly correlated with the risk of CAD in East Asians, rs2383206 and rs10757274 polymorphisms were significantly correlated with the risk of CAD in West Asians, while rs2383206, rs10757274 and rs10757278 polymorphisms were significantly correlated with the risk of CAD in Caucasians.
|
30814313 |
2019 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population.
|
28639227 |
2017 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Of thousands of chromosomal loci studied, the same locus had the strongest association with coronary artery disease in both the WTCCC and the German studies: chromosome 9p21.3 (SNP, rs1333049) (P=1.80x10(-14) and P=3.40x10(-6), respectively).
|
17634449 |
2007 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
However, the effect of rs1333049 on clinical outcomes in patients with established coronary disease has yet to be determined.
|
20400779 |
2010 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS.
|
30482443 |
2019 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
849 CAD patients undergoing revascularization (660 with CAC and 189 without CAC) were enrolled in a cohort study to test its association with cardiovascular events in CAD patients with and without CAC in a 3-year follow-up. rs1333049 was significantly associated with the incidence of cardiovascular events in non-target vessels in patients with CAC (hazard ratio = 1.44, 95%CI, 1.08-1.91, P = 0.012), but not in those without CAC.
|
24732910 |
2014 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In all, 950 patients with early onset CAD (age 56.1 +/- 9.6 years) and an independent sample of 764 patients with late onset CAD (age 70.0 +/- 8.0 years) were enrolled from the cardiac catheterization laboratories at the University of Ottawa Heart Institute from April 15, 2006, to August 15, 2008, and genotyped for the single nucleotide polymorphism rs1333049 9p21 risk variant.Angiographers were blinded to genotype.
|
20670758 |
2010 |
|
rs1333049
|
|
C |
0.900 |
GeneticVariation |
GWASDB |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We examined the prognostic values of the rs9508025 and rs1333049 variants that were found to be associated with coronary artery disease (CAD) risk in a previous Korean genome-wide association study.
|
27736948 |
2016 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A replication study and a meta-analysis of the association between the CDKN2A rs1333049 polymorphism and coronary heart disease.
|
24930384 |
2014 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The meta-analysis of the rs1333049 SNP in 12,0</span>04 cases and 28,949 controls increased the overall level of evidence for association with CAD to P=6.04x10(-10) (odds ratio, 1.24; 95% confidence interval, 1.20 to 1.29).
|
18362232 |
2008 |
|
rs1333049
|
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease.
|
29472232 |
2018 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our data from two populations show that variant rs1333049 is significantly associated with angiographically characterized CAD.
|
19135198 |
2009 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) rs1333049 (C/G) on chromosome 9p21 has been implicated in previous studies to be associated with CAD.
|
21558165 |
2011 |