|
rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs6721961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, NRF2 rs6721961 associated with CAD and severity of coronary atherosclerosis.
|
31332605 |
2020 |
|
rs72658855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A non-significant association was reported in recessive inheritance model for variant (CC+CT) vs. TT OR 0.56(0.16-1.95), P<0.36. and in dominant inheritance model for variant CC vs. (CT+TT) OR 2.8(1.07-7.34),P<0.032 .In case of allelic comparison, it was indicated that the LDLR rs2228671-T allele was associated with an increased risk of developing risk of CAD compared to C allele OR=2.4, 95% CI (1.05-5.64) P< 0.036 .Our findings showed that LDLR rs72658855 C>T gene variability is associated with an increased susceptibility to coronary artery disease in codominant inheritance model for variant CC vs. CT OR 1.7(1.1-2.6), P<0.015 and in dominant inheritance model for variant CC vs. (CT+TT) OR 1.66(1.07-2.58),P<0.0.02.
|
31613733 |
2020 |
|
rs756601757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs972655070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs1024611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
OSAS patients with homozygous MCP1 rs</span>1024611 SNP are at higher risk for CAD.
|
31388753 |
2019 |
|
rs1051339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, we characterized a second common exonic coding variant (rs1051339), which is predicted to alter LIPA signal peptide cleavage similarly to rs1051338, yet is not linked to intronic variants. rs1051339 also does not impact LIPA function in vitro and confers no coronary artery disease risk.
|
31645127 |
2019 |
|
rs1056515
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study identifies a common variant rs1056515 as a genetic marker for CAD and rare variants in LD with rs1056515 leading to decreased expression of RGS5, which contributes to atherosclerosis by impairing endothelial cell function.
|
31605122 |
2019 |
|
rs1057035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to analyze the association between SNPs in two key genes (DICER rs1057035T>C and XPO5 rs11077A>C) and coronary artery disease (CAD) risk as well as to examine their effects on circulating levels of vascular miRNAs.
|
31185329 |
2019 |
|
rs11077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to analyze the association between SNPs in two key genes (DICER rs1057035T>C and XPO5 rs11077A>C) and coronary artery disease (CAD) risk as well as to examine their effects on circulating levels of vascular miRNAs.
|
31185329 |
2019 |
|
rs11171806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2066808 and rs11171806 polymorphisms were determined in 2249 Mexican individuals (1160 with premature CAD and 1089 healthy controls).
|
31237437 |
2019 |
|
rs1137100
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, no positive findings were observed for <i>LEPR</i> rs1137100 and rs1137101 variants in overall and subgroup analyses.<b>Conclusions:</b> Our meta-analysis suggested that <i>LEP</i> rs7799039 variant might affect individual susceptibility to CAD.
|
31113873 |
2019 |
|
rs1138272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In HF patients stratified based on the underlying cause of disease, an even stronger association was observed in HF patients due to CAD, who were carriers of a combined <i>GSTP1</i>(rs1695)/<i>GSTA1</i> "risk-associated" genotype (OR = 2.8, <i>p</i> = 0.033) or a combined <i>GSTP1</i>∗Ile/Val+Val/Val (rs1695)/<i>GSTP1</i>∗AlaVal+∗ValVal (rs1138272) genotype (OR = 2.1, <i>p</i> = 0.056).
|
31275451 |
2019 |
|
rs11536879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11536879</span> and rs11536889 polymorphisms of TLR4 gene and serum TLR4 protein levels may contribute to the occurrence and development of CAD.
|
31082501 |
2019 |
|
rs12219125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> The SNPs rs9362054 near the <i>CEP162</i> gene and rs4462262 near the <i>UBE2D1</i> gene were associated with DR (OR = 1.66, <i>p</i> = 0.001; OR = 1.37, <i>p</i> = 0.031; respectively), and rs12219125 near the <i>PLXDC2</i> gene was associated (suggestive) with CAD (OR = 2.26, <i>p</i> = 0.034).
|
31130920 |
2019 |
|
rs1234314
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When we stratified eligible studies by type of disease, positive results were observed for rs17568 variant in subjects with acute coronary syndrome (ACS) (allele model: P = 0.04, OR = 0.81, 95%CI, 0.65-0.99), for rs1234314 variant in subjects with coronary artery disease (CAD) (dominant model: P = 0.04, OR = 1.16, 95%CI, 1.00-1.35), for rs3850641 variant in subjects with CAD (recessive model: P = 0.02, OR = 1.42, 95%CI, 1.05-1.90) and myocardial infarction (MI) (recessive model: P = 0.03, OR = 1.49, 95%CI, 1.05-2.11).
|
30614039 |
2019 |
|
rs12704673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel loci were associated with birthweight and adult coronary artery disease (rs2870463 in CTRB1) and with birthweight and adult waist circumference (rs12704673 in CALCR).
|
30858448 |
2019 |
|
rs146292819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It can be concluded that GG genotype of rs146292819 polymorphism and altered lipid profile act as risk factors in the pathogenesis of CAD in the Pakistani population.
|
30945099 |
2019 |
|
rs1761667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present findings revealed an association between CD36 rs1761667 polymorphism and susceptibility to hypertension and/or CAD in a southeastern Iranian population.
|
31185924 |
2019 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |
|
rs1800888
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No other significant associations were observed between ADRB1 (rs1801252, rs1801253), ADRB2 (rs1042713, rs1800888) polymorphisms and cardiovascular events or all-cause mortality in CAD patients.
|
30668166 |
2019 |
|
rs182052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regression analysis revealed an increase in prevalence of unstable angina (OR (odds ratio) = 2.55; 95%CI 1.4-4.82; p = 0.018) and coronary artery disease (OR = 1.55; 95%CI 1.15-2.09; p = 0.021) per copy of the rs182052 A allele.
|
31561637 |
2019 |
|
rs2066808
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that the rs2066808 polymorphism located near the <i>IL-23A</i> gene could increase the genetic risk of premature CAD and both studied polymorphisms could be associated with some cardiometabolic parameters in premature CAD patients and in healthy controls.
|
31237437 |
2019 |
|
rs2069705
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IFN-γ rs2069705 and rs2430561 were associated with higher level of serum IFN-γ in CAD patients (P < 0.001).
|
31141710 |
2019 |
|
rs2231142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although SUA levels were associated with premature CAD, metabolic syndrome and decreased glomerular filtration rate (eGFR), only ABCG2 rs2231142 was associated with decreased eGFR in the premature CAD group.
|
30305239 |
2019 |