Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.840 | GeneticVariation | BEFREE | In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population. | 31679296 | 2019 |
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T | 0.840 | GeneticVariation | GWASCAT | Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. | 29212778 | 2018 |
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C | 0.840 | GeneticVariation | GWASCAT | Association analyses based on false discovery rate implicate new loci for coronary artery disease. | 28714975 | 2017 |
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0.840 | GeneticVariation | BEFREE | These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA. | 28115489 | 2017 |
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0.840 | GeneticVariation | BEFREE | The CAD-associated locus 7q32.2 is unusual in that the lead variant, rs11556924, is not in strong linkage disequilibrium with any other variant and introduces a coding change in ZC3HC1, which encodes NIPA. | 27226629 | 2016 |
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C | 0.840 | GeneticVariation | GWASCAT | A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. | 26343387 | 2015 |
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T | 0.840 | GeneticVariation | GWASDB | Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. | 24262325 | 2014 |
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0.840 | GeneticVariation | BEFREE | A recent meta-analysis has described the ZC3HC1 rs11556924 polymorphism as one of the most important signals associated with coronary artery disease (CAD) in non-rheumatic Caucasian individuals. | 24286297 | 2013 |