|
rs121913409
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice.
|
30419856 |
2018 |
|
rs121913409
|
|
|
0.820 |
GeneticVariation |
BEFREE |
GC-1 exerts a notable antitumoral effect on hMet-S45Y-β-catenin HCC by inactivating Met signaling.
|
28807594 |
2017 |
|
rs121913407
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Only three HCC cases (5.6%) were found mutated at residues (G34E, S45P, P44S, T41I) important for phosphorylation and ubiquitination of beta-catenin protein.
|
25536643 |
2015 |
|
rs121913413
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Only three HCC cases (5.6%) were found mutated at residues (G34E, S45P, P44S, T41I) important for phosphorylation and ubiquitination of beta-catenin protein.
|
25536643 |
2015 |
|
rs28931589
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Only three HCC cases (5.6%) were found mutated at residues (G34E, S45P, P44S, T41I) important for phosphorylation and ubiquitination of beta-catenin protein.
|
25536643 |
2015 |
|
rs3864004
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Genotype GA (P = 0.001, OR = 0.567) and allele A (P = 0.002, OR = 0.652) of rs3864004, and genotype AG (P = 0.0004, OR = 0.495) and allele G (P = 0.001, OR = 0.596) of rs11564475 in the CTNNB1 gene were correlated with HCC compared with N-HCC patients.
|
28328801 |
2017 |
|
rs4135385
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The polymorphism rs4135385 of CTNNB1 genotype GA was associated with a higher risk for Stage III + IV HCC (modified Union for International Cancer Control) (P = 0.001, OR = 2.238).Genetic polymorphisms in the WNT2 and CTNNB1 genes were closely associated with HCC risk and progression in a Chinese Han population.
|
28328801 |
2017 |
|
rs3864004
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The CTNNB1 rs3864004 A allele was associated with a decreased risk of HCC development (P=0.049).
|
26968103 |
2016 |
|
rs4135385
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In multivariate Cox regression analysis, absence of CTNNB1 haplotype A-A at rs3864004 and rs4135385 positions and advanced tumor stage were independent poor predictors of patient survival in patients with HCC.
|
26968103 |
2016 |
|
rs11564475
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype GA (P = 0.001, OR = 0.567) and allele A (P = 0.002, OR = 0.652) of rs3864004, and genotype AG (P = 0.0004, OR = 0.495) and allele G (P = 0.001, OR = 0.596) of rs11564475 in the CTNNB1 gene were correlated with HCC compared with N-HCC patients.
|
28328801 |
2017 |