Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE There were no significant group differences in COMT Val158Met alleles and genotype frequencies between patients and controls, for all EDs pooled together [range of odds ratios (ORs): 0.96-1.04, p-values: 0.46-0.97, I<sup>2</sup>  = 0%] and when analysing separately patients with AN (ORs: 0.94-1.04, p-values: 0.31-0.61, I<sup>2</sup>  = 0%) or BN (ORs: 0.80-1.09, p-values: 0.28-0.64, I<sup>2</sup>  = 0-44%). 29057600

2017

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE Previous studies have shown that the met allele of the COMT val158met single nucleotide polymorphism (SNP) is associated with Bulimia Nervosa (BN). 25216558

2014

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. 22683321

2012

dbSNP: rs4680
rs4680
0.040 GeneticVariation BEFREE COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa. 21300128

2011