rs142014203
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs142014203
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs1445130
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs1445130
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs77600076
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs77600076
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genetic variants associated with disordered eating.
|
23568457 |
2013 |
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
There were no significant group differences in COMT Val158Met alleles and genotype frequencies between patients and controls, for all EDs pooled together [range of odds ratios (ORs): 0.96-1.04, p-values: 0.46-0.97, I<sup>2</sup> = 0%] and when analysing separately patients with AN (ORs: 0.94-1.04, p-values: 0.31-0.61, I<sup>2</sup> = 0%) or BN (ORs: 0.80-1.09, p-values: 0.28-0.64, I<sup>2</sup> = 0-44%).
|
29057600 |
2017 |
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Previous studies have shown that the met allele of the COMT val158met single nucleotide polymorphism (SNP) is associated with Bulimia Nervosa (BN).
|
25216558 |
2014 |
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders.
|
22683321 |
2012 |
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa.
|
21300128 |
2011 |
rs6265
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN).
|
17376155 |
2007 |
rs759834365
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN).
|
17376155 |
2007 |
rs6265
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In both BN and BED groups, subjects carrying the 196A/A genotype exhibited a weekly frequency of bingeing and a severity of binge eating (as assessed by the Bulimia Investigation Test Edinburgh) significantly higher than those with the 196A/G and 196G/G genotypes.
|
16901635 |
2006 |
rs759834365
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In both BN and BED groups, subjects carrying the 196A/A genotype exhibited a weekly frequency of bingeing and a severity of binge eating (as assessed by the Bulimia Investigation Test Edinburgh) significantly higher than those with the 196A/G and 196G/G genotypes.
|
16901635 |
2006 |
rs6296
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There exists preliminary evidence for association of G861C with i) antisocial alcoholism in the Finnish; ii) alcoholism in the presence of inactive aldehyde dehydrogenase 2 in the Japanese; iii) a history of suicide attempts in European-American personality disorder patients; and iv) minimum lifetime body mass index in Canadian bulimia nervosa patients.
|
12437478 |
2002 |
rs6296
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Ninety-eight women with BN were genotyped based on the G861C polymorphism of the serotonin-1B receptor gene (HTR1B).
|
11690602 |
2001 |
rs12490016
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity.
|
26458734 |
2017 |
rs1630623
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity.
|
26458734 |
2017 |
rs200889048
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three of the GWS loci identified (rs200889048, rs12490016 and rs1630623) were not previously reported by GWAS of BMI in the general population, and two of them raise interesting hypotheses: rs12490016-a regulatory variant located within LINC00880, where there are other GWAS-identified variants associated with birth size, adiposity in newborns and bulimia symptoms, which also interact with social stress in relation to birth size; rs1630623-a regulatory variant related to ALDH1A1, a gene involved in alcohol metabolism and adipocyte plasticity.
|
26458734 |
2017 |
rs287103
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>KCTD15</i> rs287103 T variant allele was associated with increased risk of bulimia nervosa (BN) (OR = 4.34 [1.47-29.52]; <i>p</i> = .003) and with scores of psychopathological scales of these patients.
|
28948079 |
2017 |
rs52820871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the obesity group, 10 different variants were identified, whereas in the binge-eating patients, only two individuals with bulimia nervosa were found to carry the I251L polymorphism, which did not correlate with weight, BMI, or psychopathological features.
|
25419636 |
2015 |
rs53576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a positive association between the G allele of OXTR rs53576 and BN.
|
25773927 |
2015 |
rs1042571
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018).
|
24831852 |
2014 |
rs13338499
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AGRP rs13338499 polymorphism was associated with lowest illness-related BMI in those with AN (p = 0.0013), and NTRK2 rs1042571 was associated with highest BMI in those with BN (p = 0.0018).
|
24831852 |
2014 |
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders.
|
22683321 |
2012 |